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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DKK3
All Species:
12.73
Human Site:
S312
Identified Species:
35
UniProt:
Q9UBP4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP4
NP_001018067.1
350
38291
S312
P
D
E
Y
E
V
G
S
F
M
E
E
V
R
Q
Chimpanzee
Pan troglodytes
XP_001171252
350
38272
S312
P
D
E
Y
E
V
G
S
F
M
E
E
V
R
Q
Rhesus Macaque
Macaca mulatta
XP_001097600
350
38402
S312
P
D
E
Y
E
V
G
S
F
M
E
E
V
R
Q
Dog
Lupus familis
XP_534060
277
30359
E253
R
Q
E
L
E
N
L
E
R
S
L
S
V
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUN9
349
38369
G312
P
D
E
Y
E
D
V
G
F
I
G
E
V
R
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511346
284
30157
E260
R
K
E
L
R
E
L
E
R
T
L
A
E
G
V
Chicken
Gallus gallus
Q90839
350
39190
S316
L
S
D
Y
E
E
S
S
V
I
Q
E
V
R
K
Frog
Xenopus laevis
NP_001121290
290
31983
S266
V
L
G
R
C
P
C
S
L
G
L
V
C
Q
P
Zebra Danio
Brachydanio rerio
NP_001083014
283
31773
L259
H
C
P
C
A
A
G
L
L
C
Q
Q
I
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.4
67.7
N.A.
82.2
N.A.
N.A.
44.2
54
40.8
36.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
98
72.5
N.A.
89.7
N.A.
N.A.
55.7
67.7
56
50
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
66.6
N.A.
N.A.
6.6
40
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
73.3
N.A.
N.A.
6.6
66.6
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
12
0
12
12
0
12
0
0
12
0
0
12
0
0
% C
% Asp:
0
45
12
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
67
0
67
23
0
23
0
0
34
56
12
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
45
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
45
12
0
12
12
0
0
12
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
23
0
0
12
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
23
% K
% Leu:
12
12
0
23
0
0
23
12
23
0
34
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
12
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
45
0
12
0
0
12
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
23
12
0
23
45
% Q
% Arg:
23
0
0
12
12
0
0
0
23
0
0
0
0
56
0
% R
% Ser:
0
12
0
0
0
0
12
56
0
12
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
12
0
0
0
0
34
12
0
12
0
0
12
67
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
56
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _