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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DKK3 All Species: 12.73
Human Site: S312 Identified Species: 35
UniProt: Q9UBP4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBP4 NP_001018067.1 350 38291 S312 P D E Y E V G S F M E E V R Q
Chimpanzee Pan troglodytes XP_001171252 350 38272 S312 P D E Y E V G S F M E E V R Q
Rhesus Macaque Macaca mulatta XP_001097600 350 38402 S312 P D E Y E V G S F M E E V R Q
Dog Lupus familis XP_534060 277 30359 E253 R Q E L E N L E R S L S V E M
Cat Felis silvestris
Mouse Mus musculus Q9QUN9 349 38369 G312 P D E Y E D V G F I G E V R Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511346 284 30157 E260 R K E L R E L E R T L A E G V
Chicken Gallus gallus Q90839 350 39190 S316 L S D Y E E S S V I Q E V R K
Frog Xenopus laevis NP_001121290 290 31983 S266 V L G R C P C S L G L V C Q P
Zebra Danio Brachydanio rerio NP_001083014 283 31773 L259 H C P C A A G L L C Q Q I Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97.4 67.7 N.A. 82.2 N.A. N.A. 44.2 54 40.8 36.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 98 72.5 N.A. 89.7 N.A. N.A. 55.7 67.7 56 50 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 66.6 N.A. N.A. 6.6 40 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 73.3 N.A. N.A. 6.6 66.6 13.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 12 0 0 0 0 0 12 0 0 0 % A
% Cys: 0 12 0 12 12 0 12 0 0 12 0 0 12 0 0 % C
% Asp: 0 45 12 0 0 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 67 0 67 23 0 23 0 0 34 56 12 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 45 0 0 0 0 0 0 % F
% Gly: 0 0 12 0 0 0 45 12 0 12 12 0 0 12 0 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 23 0 0 12 0 0 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 23 % K
% Leu: 12 12 0 23 0 0 23 12 23 0 34 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 34 0 0 0 0 12 % M
% Asn: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % N
% Pro: 45 0 12 0 0 12 0 0 0 0 0 0 0 0 12 % P
% Gln: 0 12 0 0 0 0 0 0 0 0 23 12 0 23 45 % Q
% Arg: 23 0 0 12 12 0 0 0 23 0 0 0 0 56 0 % R
% Ser: 0 12 0 0 0 0 12 56 0 12 0 12 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % T
% Val: 12 0 0 0 0 34 12 0 12 0 0 12 67 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 56 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _