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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DKK3 All Species: 13.03
Human Site: Y158 Identified Species: 35.83
UniProt: Q9UBP4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBP4 NP_001018067.1 350 38291 Y158 E D C G P S M Y C Q F A S F Q
Chimpanzee Pan troglodytes XP_001171252 350 38272 Y158 E D C G P S K Y C Q F A S F Q
Rhesus Macaque Macaca mulatta XP_001097600 350 38402 Y158 E D C G P S K Y C Q F A S F Q
Dog Lupus familis XP_534060 277 30359 C113 C T R D G E C C G D Q L C V W
Cat Felis silvestris
Mouse Mus musculus Q9QUN9 349 38369 Y158 E D C G P T R Y C Q F S S F K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511346 284 30157 S120 G L C A K D A S P G G D G T I
Chicken Gallus gallus Q90839 350 39190 Q161 S T F E Y K C Q P C K T Q H T
Frog Xenopus laevis NP_001121290 290 31983 G126 K N T D N R T G S T L Y S Q T
Zebra Danio Brachydanio rerio NP_001083014 283 31773 H118 D N K T G K T H F S R T L I Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97.4 67.7 N.A. 82.2 N.A. N.A. 44.2 54 40.8 36.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 98 72.5 N.A. 89.7 N.A. N.A. 55.7 67.7 56 50 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 0 N.A. 73.3 N.A. N.A. 6.6 0 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 0 N.A. 93.3 N.A. N.A. 6.6 0 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 12 0 0 0 0 34 0 0 0 % A
% Cys: 12 0 56 0 0 0 23 12 45 12 0 0 12 0 0 % C
% Asp: 12 45 0 23 0 12 0 0 0 12 0 12 0 0 0 % D
% Glu: 45 0 0 12 0 12 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 12 0 0 0 0 0 12 0 45 0 0 45 0 % F
% Gly: 12 0 0 45 23 0 0 12 12 12 12 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 12 0 0 0 0 0 12 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 12 % I
% Lys: 12 0 12 0 12 23 23 0 0 0 12 0 0 0 12 % K
% Leu: 0 12 0 0 0 0 0 0 0 0 12 12 12 0 0 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 23 0 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 45 0 0 0 23 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 12 0 45 12 0 12 12 45 % Q
% Arg: 0 0 12 0 0 12 12 0 0 0 12 0 0 0 0 % R
% Ser: 12 0 0 0 0 34 0 12 12 12 0 12 56 0 0 % S
% Thr: 0 23 12 12 0 12 23 0 0 12 0 23 0 12 23 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % W
% Tyr: 0 0 0 0 12 0 0 45 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _