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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEY2
All Species:
13.64
Human Site:
S67
Identified Species:
33.33
UniProt:
Q9UBP5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP5
NP_036391.1
337
35808
S67
R
R
D
R
I
N
N
S
L
S
E
L
R
R
L
Chimpanzee
Pan troglodytes
XP_527497
341
36267
L71
I
N
N
S
L
S
E
L
R
R
L
V
P
T
A
Rhesus Macaque
Macaca mulatta
XP_001107591
337
35790
S67
R
R
D
R
I
N
N
S
L
S
E
L
R
R
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUS4
339
35855
S67
R
R
D
R
I
N
N
S
L
S
E
L
R
R
L
Rat
Rattus norvegicus
Q04666
281
29603
R35
P
K
T
A
S
E
H
R
K
S
S
K
P
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520843
109
12221
Chicken
Gallus gallus
O57337
290
31053
E44
K
S
S
K
P
I
M
E
K
R
R
R
A
R
I
Frog
Xenopus laevis
Q9I8A3
294
32117
R48
Q
I
L
A
R
K
R
R
R
G
I
I
E
K
R
Zebra Danio
Brachydanio rerio
Q9I9L0
324
34311
S67
R
R
D
R
I
N
N
S
L
S
E
L
R
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KM13
425
46797
L120
R
D
R
I
N
S
S
L
T
E
L
K
R
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
99.4
N.A.
N.A.
93.5
29.3
N.A.
30.2
29
51.6
77.4
N.A.
32.7
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
100
N.A.
N.A.
95.8
41.2
N.A.
31.7
43.3
66.7
86.3
N.A.
44.7
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
N.A.
N.A.
100
6.6
N.A.
0
6.6
0
100
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
N.A.
N.A.
100
26.6
N.A.
0
26.6
20
100
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
40
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
10
0
10
40
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
10
40
10
0
0
0
0
10
10
0
10
10
% I
% Lys:
10
10
0
10
0
10
0
0
20
0
0
20
0
10
0
% K
% Leu:
0
0
10
0
10
0
0
20
40
0
20
40
0
10
40
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
10
0
10
40
40
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
0
0
0
0
0
0
0
20
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
40
10
40
10
0
10
20
20
20
10
10
50
50
10
% R
% Ser:
0
10
10
10
10
20
10
40
0
50
10
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _