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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL1
All Species:
19.09
Human Site:
S27
Identified Species:
28
UniProt:
Q9UBP6
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP6
NP_005362.3
276
31471
S27
Y
Y
R
Q
R
A
H
S
N
P
M
A
D
H
T
Chimpanzee
Pan troglodytes
XP_001167352
301
34100
S52
Y
Y
R
Q
R
A
H
S
N
P
I
A
D
H
T
Rhesus Macaque
Macaca mulatta
XP_001116496
301
34160
S52
Y
Y
R
Q
R
A
H
S
N
P
M
A
D
H
T
Dog
Lupus familis
XP_849422
247
28132
T27
A
P
L
T
Q
N
K
T
H
D
D
P
K
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z120
268
30585
Y31
M
A
D
H
T
L
R
Y
P
V
K
P
E
E
M
Rat
Rattus norvegicus
XP_001054797
267
30550
Y30
M
A
D
H
T
L
R
Y
P
V
K
P
E
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516298
226
25512
W14
V
R
P
E
D
M
D
W
S
E
L
F
P
A
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU94
273
31824
S29
Y
Y
R
Q
R
A
H
S
N
P
M
A
D
H
T
Zebra Danio
Brachydanio rerio
Q5XJ57
241
27917
Y27
M
A
D
H
T
F
Q
Y
P
V
C
P
E
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77263
256
29406
G28
N
P
T
S
A
V
T
G
L
P
Q
K
R
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23126
256
30022
K27
T
V
P
G
L
P
Q
K
K
H
Y
R
Q
R
A
Sea Urchin
Strong. purpuratus
XP_790960
406
47124
A93
I
N
A
K
S
S
L
A
F
F
K
N
N
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
B6SHG7
255
29101
P27
R
A
R
A
H
S
N
P
L
S
D
S
H
F
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXB7
251
28800
S28
F
Y
R
A
R
A
H
S
N
P
L
S
D
S
H
Baker's Yeast
Sacchar. cerevisiae
Q12009
286
33373
N34
E
L
K
H
V
K
I
N
E
S
S
L
V
Q
E
Red Bread Mold
Neurospora crassa
Q7RZC1
293
33715
A38
F
Y
R
Q
R
A
H
A
N
P
F
S
D
H
S
Conservation
Percent
Protein Identity:
100
90.6
90.6
81.5
N.A.
88
88.4
N.A.
64.8
N.A.
69.5
67.7
N.A.
47.4
N.A.
50.7
42.3
Protein Similarity:
100
91.3
91
83.6
N.A.
92.3
90.9
N.A.
72
N.A.
80
76.4
N.A.
59.7
N.A.
64.8
51.2
P-Site Identity:
100
93.3
100
0
N.A.
0
0
N.A.
0
N.A.
100
0
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
100
20
N.A.
6.6
6.6
N.A.
20
N.A.
100
6.6
N.A.
13.3
N.A.
0
33.3
Percent
Protein Identity:
N.A.
52.5
N.A.
50
46.8
48.8
Protein Similarity:
N.A.
68.4
N.A.
68.4
61.5
66.2
P-Site Identity:
N.A.
6.6
N.A.
60
0
66.6
P-Site Similarity:
N.A.
26.6
N.A.
80
13.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
25
7
13
7
38
0
13
0
0
0
25
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
19
0
7
0
7
0
0
7
13
0
38
7
0
% D
% Glu:
7
0
0
7
0
0
0
0
7
7
0
0
19
13
7
% E
% Phe:
13
0
0
0
0
7
0
0
7
7
7
7
0
7
7
% F
% Gly:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
25
7
0
38
0
7
7
0
0
7
32
7
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
7
7
0
7
7
7
7
0
19
7
7
0
7
% K
% Leu:
0
7
7
0
7
13
7
0
13
0
13
7
0
0
0
% L
% Met:
19
0
0
0
0
7
0
0
0
0
19
0
0
0
19
% M
% Asn:
7
7
0
0
0
7
7
7
38
0
0
7
7
0
0
% N
% Pro:
0
13
13
0
0
7
0
7
19
44
0
25
7
0
7
% P
% Gln:
0
0
0
32
7
0
13
0
0
0
7
0
7
13
0
% Q
% Arg:
7
7
44
0
38
0
13
0
0
0
0
7
7
7
0
% R
% Ser:
0
0
0
7
7
13
0
32
7
13
7
19
0
7
13
% S
% Thr:
7
0
7
7
19
0
7
7
0
0
0
0
0
7
25
% T
% Val:
7
7
0
0
7
7
0
0
0
19
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
25
38
0
0
0
0
0
19
0
0
7
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _