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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3K
All Species:
22.42
Human Site:
S166
Identified Species:
41.11
UniProt:
Q9UBQ5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBQ5
NP_037366.1
218
25060
S166
A
E
M
L
G
D
L
S
D
S
Q
L
K
V
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082499
185
21262
D134
E
M
L
G
D
L
S
D
S
Q
L
K
V
W
M
Dog
Lupus familis
XP_867463
192
22077
K140
G
F
E
D
S
V
R
K
Y
S
Q
L
K
V
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBZ5
218
25068
T166
A
E
M
L
G
D
L
T
D
N
Q
L
K
V
W
Rat
Rattus norvegicus
NP_001099712
107
12340
T55
A
E
M
L
G
D
L
T
D
N
Q
L
R
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519426
194
21370
S142
A
E
M
L
G
D
L
S
D
N
Q
L
K
L
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GNI4
218
25112
S166
A
E
M
L
G
D
L
S
E
P
Q
L
R
V
W
Zebra Danio
Brachydanio rerio
Q567V6
219
25408
L167
A
E
M
L
G
D
P
L
D
T
Q
V
K
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2D9
222
25647
E170
K
E
L
L
G
G
I
E
D
S
T
L
E
S
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUP3
240
27013
S182
S
R
L
L
G
G
A
S
D
K
E
V
T
A
L
Sea Urchin
Strong. purpuratus
XP_792388
217
24777
D165
G
E
L
L
G
V
S
D
D
T
E
L
K
R
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZA3
226
25710
L171
V
N
M
D
G
A
S
L
D
K
F
I
E
Q
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S2R9
237
26733
S181
S
W
L
G
L
N
N
S
E
A
T
T
Q
F
I
Conservation
Percent
Protein Identity:
100
N.A.
84.8
88
N.A.
98.6
46.7
N.A.
61
N.A.
90.3
84
N.A.
45.9
N.A.
35.4
53.6
Protein Similarity:
100
N.A.
84.8
88
N.A.
100
48.6
N.A.
67.8
N.A.
97.2
94
N.A.
65.3
N.A.
58.3
70.1
P-Site Identity:
100
N.A.
0
40
N.A.
86.6
80
N.A.
86.6
N.A.
80
73.3
N.A.
46.6
N.A.
26.6
46.6
P-Site Similarity:
100
N.A.
6.6
40
N.A.
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
66.6
N.A.
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
N.A.
29.9
Protein Similarity:
N.A.
N.A.
N.A.
52.2
N.A.
48.1
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
0
0
8
8
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
47
0
16
70
0
0
0
0
0
0
% D
% Glu:
8
62
8
0
0
0
0
8
16
0
16
0
16
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
16
0
0
16
77
16
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% I
% Lys:
8
0
0
0
0
0
0
8
0
16
0
8
47
0
0
% K
% Leu:
0
0
39
70
8
8
39
16
0
0
8
62
0
8
8
% L
% Met:
0
8
54
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
8
8
0
0
24
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
54
0
8
8
8
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
0
0
16
8
0
% R
% Ser:
16
0
0
0
8
0
24
39
8
24
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
16
0
16
16
8
8
0
0
% T
% Val:
8
0
0
0
0
16
0
0
0
0
0
16
8
47
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
70
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _