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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3K
All Species:
13.64
Human Site:
S191
Identified Species:
25
UniProt:
Q9UBQ5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBQ5
NP_037366.1
218
25060
S191
S
G
Q
I
F
I
C
S
Q
E
E
S
I
K
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082499
185
21262
Q159
G
Q
I
F
I
C
S
Q
E
E
S
I
K
P
K
Dog
Lupus familis
XP_867463
192
22077
S165
S
G
Q
I
F
I
C
S
Q
E
E
S
I
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBZ5
218
25068
S191
S
G
Q
V
F
I
C
S
Q
E
E
S
I
K
P
Rat
Rattus norvegicus
NP_001099712
107
12340
S80
S
G
Q
V
F
I
C
S
Q
E
E
S
I
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519426
194
21370
N167
A
G
Q
I
F
I
C
N
Q
E
E
S
I
K
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GNI4
218
25112
N191
N
G
K
I
F
V
C
N
Q
E
E
N
I
K
P
Zebra Danio
Brachydanio rerio
Q567V6
219
25408
N192
D
G
Q
I
F
I
H
N
Q
E
E
S
V
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2D9
222
25647
M195
Q
G
L
V
I
V
A
M
Q
D
D
K
I
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUP3
240
27013
A207
N
G
D
V
F
F
V
A
N
H
E
G
T
I
K
Sea Urchin
Strong. purpuratus
XP_792388
217
24777
N190
G
G
K
V
F
I
S
N
Q
E
E
S
V
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZA3
226
25710
P196
E
G
G
S
I
V
L
P
Q
N
E
F
N
H
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S2R9
237
26733
N206
D
V
V
Q
I
P
K
N
A
D
N
E
A
R
K
Conservation
Percent
Protein Identity:
100
N.A.
84.8
88
N.A.
98.6
46.7
N.A.
61
N.A.
90.3
84
N.A.
45.9
N.A.
35.4
53.6
Protein Similarity:
100
N.A.
84.8
88
N.A.
100
48.6
N.A.
67.8
N.A.
97.2
94
N.A.
65.3
N.A.
58.3
70.1
P-Site Identity:
100
N.A.
6.6
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
66.6
73.3
N.A.
26.6
N.A.
20
53.3
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
100
N.A.
100
86.6
N.A.
53.3
N.A.
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
N.A.
29.9
Protein Similarity:
N.A.
N.A.
N.A.
52.2
N.A.
48.1
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
47
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
0
0
0
0
0
0
16
8
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
8
70
77
8
0
0
0
% E
% Phe:
0
0
0
8
70
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
16
85
8
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
8
39
31
54
0
0
0
0
0
8
54
8
0
% I
% Lys:
0
0
16
0
0
0
8
0
0
0
0
8
8
70
24
% K
% Leu:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
0
39
8
8
8
8
8
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
62
% P
% Gln:
8
8
47
8
0
0
0
8
77
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
31
0
0
8
0
0
16
31
0
0
8
54
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
16
% T
% Val:
0
8
8
39
0
24
8
0
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _