Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF3K All Species: 22.73
Human Site: Y32 Identified Species: 41.67
UniProt: Q9UBQ5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBQ5 NP_037366.1 218 25060 Y32 N L A T L E R Y V E T Q A K E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082499 185 21262 K13 Q M R A N V G K L L K G I D R
Dog Lupus familis XP_867463 192 22077 D19 G K L L K G I D R Y N P E N L
Cat Felis silvestris
Mouse Mus musculus Q9DBZ5 218 25068 Y32 N L A T L E R Y V E T Q A K E
Rat Rattus norvegicus NP_001099712 107 12340
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519426 194 21370 G19 R L R P P R G G A S C L R R R
Chicken Gallus gallus
Frog Xenopus laevis Q6GNI4 218 25112 Y32 N L A T L E R Y V E T Q A K E
Zebra Danio Brachydanio rerio Q567V6 219 25408 Y33 N L A T L E R Y V D T Q A R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2D9 222 25647 Y36 H L K T L E S Y V Q D Q A K N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XUP3 240 27013 C31 N V A D L A A C V Q A M V N E
Sea Urchin Strong. purpuratus XP_792388 217 24777 Y31 N L A L L E N Y V E I Q G R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SZA3 226 25710 E34 P E I L P D L E N Y V N V T S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S2R9 237 26733 Y34 A A G T L E A Y L T Q Q C E E
Conservation
Percent
Protein Identity: 100 N.A. 84.8 88 N.A. 98.6 46.7 N.A. 61 N.A. 90.3 84 N.A. 45.9 N.A. 35.4 53.6
Protein Similarity: 100 N.A. 84.8 88 N.A. 100 48.6 N.A. 67.8 N.A. 97.2 94 N.A. 65.3 N.A. 58.3 70.1
P-Site Identity: 100 N.A. 0 0 N.A. 100 0 N.A. 6.6 N.A. 100 86.6 N.A. 60 N.A. 33.3 66.6
P-Site Similarity: 100 N.A. 13.3 0 N.A. 100 0 N.A. 13.3 N.A. 100 100 N.A. 73.3 N.A. 46.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 30.9 N.A. 29.9
Protein Similarity: N.A. N.A. N.A. 52.2 N.A. 48.1
P-Site Identity: N.A. N.A. N.A. 0 N.A. 40
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 47 8 0 8 16 0 8 0 8 0 39 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 0 8 0 0 % C
% Asp: 0 0 0 8 0 8 0 8 0 8 8 0 0 8 0 % D
% Glu: 0 8 0 0 0 54 0 8 0 31 0 0 8 8 54 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 8 16 8 0 0 0 8 8 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 8 0 0 0 8 0 8 0 0 % I
% Lys: 0 8 8 0 8 0 0 8 0 0 8 0 0 31 0 % K
% Leu: 0 54 8 24 62 0 8 0 16 8 0 8 0 0 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 47 0 0 0 8 0 8 0 8 0 8 8 0 16 8 % N
% Pro: 8 0 0 8 16 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 16 8 54 0 0 0 % Q
% Arg: 8 0 16 0 0 8 31 0 8 0 0 0 8 24 16 % R
% Ser: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % S
% Thr: 0 0 0 47 0 0 0 0 0 8 31 0 0 8 0 % T
% Val: 0 8 0 0 0 8 0 0 54 0 8 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 54 0 16 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _