KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UPB1
All Species:
4.55
Human Site:
S375
Identified Species:
8.33
UniProt:
Q9UBR1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBR1
NP_057411.1
384
43166
S375
E
L
A
E
A
V
K
S
N
Y
S
P
T
I
V
Chimpanzee
Pan troglodytes
XP_001170826
384
43229
S375
E
L
A
E
A
V
K
S
N
Y
S
P
T
I
V
Rhesus Macaque
Macaca mulatta
XP_001095304
384
43190
P375
E
L
A
E
A
V
K
P
N
Y
R
P
T
I
V
Dog
Lupus familis
XP_543524
384
43074
P375
E
L
A
E
A
I
K
P
N
Y
S
P
N
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC97
393
43919
P375
E
L
A
E
A
V
K
P
N
Y
S
P
N
I
V
Rat
Rattus norvegicus
Q03248
393
44024
P375
E
L
A
E
A
V
K
P
N
Y
S
P
N
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415242
383
42698
P374
K
L
A
E
A
V
Q
P
C
F
T
P
N
I
I
Frog
Xenopus laevis
NP_001087502
383
43161
P374
E
L
T
K
A
T
Q
P
D
F
K
P
N
I
V
Zebra Danio
Brachydanio rerio
NP_955910
384
43309
H375
E
L
K
K
A
I
Q
H
D
F
K
P
N
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649732
386
43781
H376
S
F
K
K
A
S
E
H
G
F
K
P
Q
I
I
Honey Bee
Apis mellifera
XP_392773
379
42939
K369
E
L
N
E
Y
V
E
K
N
I
K
P
L
E
K
Nematode Worm
Caenorhab. elegans
NP_495261
387
43178
P377
K
I
T
E
V
S
N
P
D
Y
R
P
D
I
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYF5
326
36438
V318
R
R
P
D
L
Y
K
V
L
L
T
M
D
G
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.6
89.5
N.A.
83.7
82.6
N.A.
N.A.
79.4
78.6
76
N.A.
63.7
61.9
61.7
N.A.
Protein Similarity:
100
97.4
98.6
95.5
N.A.
89
89.3
N.A.
N.A.
88.2
89
89
N.A.
77.9
76.5
76.7
N.A.
P-Site Identity:
100
100
86.6
73.3
N.A.
86.6
86.6
N.A.
N.A.
46.6
40
26.6
N.A.
20
40
26.6
N.A.
P-Site Similarity:
100
100
86.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
80
66.6
73.3
N.A.
46.6
46.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
54
0
77
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
24
0
0
0
16
0
0
% D
% Glu:
70
0
0
70
0
0
16
0
0
0
0
0
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
31
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
16
0
0
0
8
0
0
0
70
16
% I
% Lys:
16
0
16
24
0
0
54
8
0
0
31
0
0
0
8
% K
% Leu:
0
77
0
0
8
0
0
0
8
8
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
8
0
0
0
8
0
54
0
0
0
47
0
8
% N
% Pro:
0
0
8
0
0
0
0
54
0
0
0
93
0
0
0
% P
% Gln:
0
0
0
0
0
0
24
0
0
0
0
0
8
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
0
0
16
0
0
0
8
% R
% Ser:
8
0
0
0
0
16
0
16
0
0
39
0
0
0
0
% S
% Thr:
0
0
16
0
0
8
0
0
0
0
16
0
24
0
0
% T
% Val:
0
0
0
0
8
54
0
8
0
0
0
0
0
16
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
54
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _