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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTSZ All Species: 26.06
Human Site: S97 Identified Species: 63.7
UniProt: Q9UBR2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBR2 NP_001327.2 303 33868 S97 G S C W A H A S T S A M A D R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_854795 375 41541 S169 G S C W A H G S T S A M A D R
Cat Felis silvestris
Mouse Mus musculus Q9WUU7 306 33978 S99 G S C W A H G S T S A M A D R
Rat Rattus norvegicus Q9R1T3 306 34176 S99 G S C W A H G S T S A L A D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09648 218 23945 T14 W R E K G Y V T P V K D Q G Q
Frog Xenopus laevis NP_001088101 296 32990 S88 G S C W A H G S T S A M A D R
Zebra Danio Brachydanio rerio NP_001006043 301 33586 S89 G S C W A H G S T S A L A D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P43510 379 42386 A135 S S C G S C W A F G A V E A M
Sea Urchin Strong. purpuratus XP_788187 293 31563 T84 G S C W A M G T T S A L A D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65493 355 39599 H81 V F R E N L M H I D Q R N N E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 67.7 N.A. 83 83.9 N.A. N.A. 25 71.6 64 N.A. N.A. N.A. 23.4 56.1
Protein Similarity: 100 N.A. N.A. 72.2 N.A. 89.5 90.1 N.A. N.A. 38.2 79.8 76.5 N.A. N.A. N.A. 36.4 70.6
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 93.3 86.6 N.A. N.A. 0 93.3 86.6 N.A. N.A. N.A. 20 73.3
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 20 93.3 93.3 N.A. N.A. N.A. 40 86.6
Percent
Protein Identity: N.A. N.A. N.A. 20 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 70 0 10 10 0 0 80 0 70 10 0 % A
% Cys: 0 0 80 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 10 0 70 0 % D
% Glu: 0 0 10 10 0 0 0 0 0 0 0 0 10 0 10 % E
% Phe: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 70 0 0 10 10 0 60 0 0 10 0 0 0 10 0 % G
% His: 0 0 0 0 0 60 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 0 0 30 0 0 0 % L
% Met: 0 0 0 0 0 10 10 0 0 0 0 40 0 0 10 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 10 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 10 % Q
% Arg: 0 10 10 0 0 0 0 0 0 0 0 10 0 0 70 % R
% Ser: 10 80 0 0 10 0 0 60 0 70 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 20 70 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 0 10 0 0 10 0 10 0 0 0 % V
% Trp: 10 0 0 70 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _