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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSZ
All Species:
8.79
Human Site:
Y280
Identified Species:
21.48
UniProt:
Q9UBR2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBR2
NP_001327.2
303
33868
Y280
L
R
I
V
T
S
T
Y
K
D
G
K
G
A
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854795
375
41541
Y352
M
R
I
V
T
S
T
Y
K
D
G
K
G
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUU7
306
33978
T282
W
M
R
I
V
T
S
T
Y
K
G
G
T
G
D
Rat
Rattus norvegicus
Q9R1T3
306
34176
T282
W
M
R
I
V
T
S
T
Y
K
G
G
T
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09648
218
23945
Y196
E
K
W
G
D
K
G
Y
I
Y
M
A
K
D
R
Frog
Xenopus laevis
NP_001088101
296
32990
A271
W
L
R
I
V
T
S
A
Y
K
G
G
K
G
A
Zebra Danio
Brachydanio rerio
NP_001006043
301
33586
A272
W
L
R
I
V
T
S
A
Y
K
G
G
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P43510
379
42386
D344
F
R
I
L
R
G
V
D
E
C
G
I
E
S
G
Sea Urchin
Strong. purpuratus
XP_788187
293
31563
S267
G
W
V
R
I
V
T
S
A
Y
K
S
G
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65493
355
39599
G309
V
G
Y
G
S
S
K
G
S
D
Y
V
I
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
67.7
N.A.
83
83.9
N.A.
N.A.
25
71.6
64
N.A.
N.A.
N.A.
23.4
56.1
Protein Similarity:
100
N.A.
N.A.
72.2
N.A.
89.5
90.1
N.A.
N.A.
38.2
79.8
76.5
N.A.
N.A.
N.A.
36.4
70.6
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
6.6
6.6
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
26.6
26.6
N.A.
N.A.
20
26.6
26.6
N.A.
N.A.
N.A.
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
10
0
0
10
0
30
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
30
0
0
0
10
10
% D
% Glu:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
20
0
10
10
10
0
0
70
40
30
40
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
30
40
10
0
0
0
10
0
0
10
10
0
0
% I
% Lys:
0
10
0
0
0
10
10
0
20
40
10
20
20
0
10
% K
% Leu:
10
20
0
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
10
20
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
30
40
10
10
0
0
0
0
0
0
0
0
0
20
% R
% Ser:
0
0
0
0
10
30
40
10
10
0
0
10
10
10
30
% S
% Thr:
0
0
0
0
20
40
30
20
0
0
0
0
20
0
0
% T
% Val:
10
0
10
20
40
10
10
0
0
0
0
10
0
10
0
% V
% Trp:
40
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
30
40
20
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _