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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHX3 All Species: 10
Human Site: S238 Identified Species: 20
UniProt: Q9UBR4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBR4 NP_055379.1 397 43358 S238 M K R S R G G S K S D K D S V
Chimpanzee Pan troglodytes Q5IS44 406 44776 F252 G A R R H A F F R S P R R M R
Rhesus Macaque Macaca mulatta XP_001096075 397 43396 S238 M K R S R G G S K S D K D S V
Dog Lupus familis XP_849415 462 49758 Q303 G L D M R V V Q L D K D S V Q
Cat Felis silvestris
Mouse Mus musculus P50481 400 43991 S241 M K R S R G S S K S D K D S I
Rat Rattus norvegicus P61376 402 44369 A246 K Q L S A L G A R R H A F F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P53412 395 43787 K236 K R S R G T S K S D K D S I Q
Frog Xenopus laevis P36200 395 44013 K236 K R S R G N S K S D K D S I Q
Zebra Danio Brachydanio rerio Q90421 398 44208 K236 K R S R G T S K S D K D S T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRC7 275 31013 H122 D R V L C K A H Y L E T V E G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P20271 351 40037 A198 S L E T L K Q A Y Q T S S K P
Sea Urchin Strong. purpuratus XP_780701 485 54161 S296 I K R V N E A S S P A S G P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.5 98.7 71.4 N.A. 90.7 29.1 N.A. N.A. 79.3 77 73.8 N.A. 28.4 N.A. 43.3 42
Protein Similarity: 100 47.7 98.9 74.4 N.A. 94 46.2 N.A. N.A. 86.9 85.3 82.9 N.A. 40.2 N.A. 54.6 54
P-Site Identity: 100 13.3 100 6.6 N.A. 86.6 13.3 N.A. N.A. 0 0 0 N.A. 0 N.A. 0 20
P-Site Similarity: 100 26.6 100 6.6 N.A. 93.3 33.3 N.A. N.A. 6.6 6.6 13.3 N.A. 13.3 N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 17 17 0 0 9 9 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 0 0 0 0 0 34 25 34 25 0 0 % D
% Glu: 0 0 9 0 0 9 0 0 0 0 9 0 0 9 9 % E
% Phe: 0 0 0 0 0 0 9 9 0 0 0 0 9 9 0 % F
% Gly: 17 0 0 0 25 25 25 0 0 0 0 0 9 0 9 % G
% His: 0 0 0 0 9 0 0 9 0 0 9 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 17 9 % I
% Lys: 34 34 0 0 0 17 0 25 25 0 34 25 0 9 0 % K
% Leu: 0 17 9 9 9 9 0 0 9 9 0 0 0 0 0 % L
% Met: 25 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 9 0 0 9 9 % P
% Gln: 0 9 0 0 0 0 9 9 0 9 0 0 0 0 34 % Q
% Arg: 0 34 42 34 34 0 0 0 17 9 0 9 9 0 17 % R
% Ser: 9 0 25 34 0 0 34 34 34 34 0 17 42 25 0 % S
% Thr: 0 0 0 9 0 17 0 0 0 0 9 9 0 9 0 % T
% Val: 0 0 9 9 0 9 9 0 0 0 0 0 9 9 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _