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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHX3 All Species: 26.36
Human Site: S256 Identified Species: 52.73
UniProt: Q9UBR4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBR4 NP_055379.1 397 43358 S256 Q D S D A E V S F P D E P S L
Chimpanzee Pan troglodytes Q5IS44 406 44776 L270 D R L E P G E L I P N G P F S
Rhesus Macaque Macaca mulatta XP_001096075 397 43396 S256 Q D S D A E V S F P D E P S L
Dog Lupus familis XP_849415 462 49758 S321 Q D S D A D V S F T D E P T M
Cat Felis silvestris
Mouse Mus musculus P50481 400 43991 S259 Q D S D A E V S F T D E P S M
Rat Rattus norvegicus P61376 402 44369 R264 R M R P L G G R L D E S E M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P53412 395 43787 S254 P D S D A E V S F T D E P S M
Frog Xenopus laevis P36200 395 44013 S254 P D S D A E V S F T D E P S M
Zebra Danio Brachydanio rerio Q90421 398 44208 S254 M D S D A E V S F T D E P P M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRC7 275 31013 G140 S S D E G C D G D G Y H K S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P20271 351 40037 E216 V R E Q L A S E T G L D M R V
Sea Urchin Strong. purpuratus XP_780701 485 54161 S314 S P V K L E P S D L D D T T V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.5 98.7 71.4 N.A. 90.7 29.1 N.A. N.A. 79.3 77 73.8 N.A. 28.4 N.A. 43.3 42
Protein Similarity: 100 47.7 98.9 74.4 N.A. 94 46.2 N.A. N.A. 86.9 85.3 82.9 N.A. 40.2 N.A. 54.6 54
P-Site Identity: 100 13.3 100 73.3 N.A. 86.6 6.6 N.A. N.A. 80 80 73.3 N.A. 6.6 N.A. 0 20
P-Site Similarity: 100 26.6 100 93.3 N.A. 93.3 20 N.A. N.A. 86.6 86.6 80 N.A. 13.3 N.A. 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 59 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 59 9 59 0 9 9 0 17 9 67 17 0 0 0 % D
% Glu: 0 0 9 17 0 59 9 9 0 0 9 59 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 59 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 9 17 9 9 0 17 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 9 % K
% Leu: 0 0 9 0 25 0 0 9 9 9 9 0 0 0 25 % L
% Met: 9 9 0 0 0 0 0 0 0 0 0 0 9 9 42 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 17 9 0 9 9 0 9 0 0 25 0 0 67 9 0 % P
% Gln: 34 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 17 9 0 0 0 0 9 0 0 0 0 0 9 0 % R
% Ser: 17 9 59 0 0 0 9 67 0 0 0 9 0 50 9 % S
% Thr: 0 0 0 0 0 0 0 0 9 42 0 0 9 17 0 % T
% Val: 9 0 9 0 0 0 59 0 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _