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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
31.82
Human Site:
S377
Identified Species:
50
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
S377
S
P
D
D
T
A
L
S
E
S
A
N
Q
A
F
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
S377
S
P
D
D
T
A
L
S
E
S
A
N
Q
A
F
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
S404
S
P
D
D
T
A
L
S
E
S
A
N
Q
A
F
Dog
Lupus familis
XP_851971
482
53401
S375
S
P
D
D
T
A
L
S
E
S
A
N
Q
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
S377
S
P
D
D
T
A
L
S
E
S
A
N
Q
A
F
Rat
Rattus norvegicus
P67999
525
59113
S401
S
P
D
D
S
T
L
S
E
S
A
N
Q
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
S358
S
P
D
D
S
T
L
S
E
S
A
N
Q
V
F
Chicken
Gallus gallus
P18652
752
84421
A388
S
P
G
I
P
P
S
A
G
A
H
Q
L
F
R
Frog
Xenopus laevis
P10665
733
82620
A370
S
P
G
I
P
P
S
A
G
A
H
Q
L
F
R
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
S374
D
S
P
G
I
P
P
S
A
N
A
H
Q
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
E1008
L
P
E
E
Y
Y
S
E
L
P
L
P
E
E
D
Honey Bee
Apis mellifera
XP_395876
456
51514
A352
P
P
F
R
P
T
L
A
S
E
D
D
V
S
Q
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
A412
S
P
A
L
P
A
S
A
N
G
H
E
I
F
R
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
S382
S
P
D
D
S
M
L
S
E
S
A
N
Q
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
L366
L
S
N
E
A
H
A
L
L
K
G
L
L
Q
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
100
100
100
N.A.
100
80
N.A.
80
13.3
13.3
26.6
N.A.
6.6
13.3
20
80
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
86.6
26.6
26.6
40
N.A.
26.6
33.3
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
40
7
27
7
14
60
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
54
54
0
0
0
0
0
0
7
7
0
0
7
% D
% Glu:
0
0
7
14
0
0
0
7
54
7
0
7
7
7
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
20
60
% F
% Gly:
0
0
14
7
0
0
0
0
14
7
7
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
20
7
0
0
0
% H
% Ile:
0
0
0
14
7
0
0
0
0
0
0
0
7
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% K
% Leu:
14
0
0
7
0
0
60
7
14
0
7
7
20
7
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
7
7
0
54
0
0
0
% N
% Pro:
7
87
7
0
27
20
7
0
0
7
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
14
60
7
7
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
20
% R
% Ser:
74
14
0
0
20
0
27
60
7
54
0
0
0
7
0
% S
% Thr:
0
0
0
0
34
20
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _