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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6KB2 All Species: 10.61
Human Site: S438 Identified Species: 16.67
UniProt: Q9UBS0 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBS0 NP_003943.2 482 53483 S438 E G F R P S P S L P E P T E L
Chimpanzee Pan troglodytes XP_001172909 482 53404 S438 E G F R P S P S L P E P T E L
Rhesus Macaque Macaca mulatta XP_001117937 512 56562 S465 E G F R P S P S L P E P M E P
Dog Lupus familis XP_851971 482 53401 G436 E G F R P S S G P P E P M E P
Cat Felis silvestris
Mouse Mus musculus Q9Z1M4 485 53520 G438 E G F R P S P G P P E P M E P
Rat Rattus norvegicus P67999 525 59113 S462 D F W G R G A S A S T A N P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509850 482 54026 S419 D F W G R G A S A S T V T T Q
Chicken Gallus gallus P18652 752 84421 C449 G V G S Y S V C K R C I H K T
Frog Xenopus laevis P10665 733 82620 K431 V G S Y S V C K R C V H K G T
Zebra Danio Brachydanio rerio Q6PFQ0 740 83378 K435 V G S Y S I C K R C I H R V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3I5 1207 137026 M1069 K A S L R V L M Q Q L P P P G
Honey Bee Apis mellifera XP_395876 456 51514 R413 V I N A R S P R R G N M R G F
Nematode Worm Caenorhab. elegans Q21734 784 88102 M473 S V V H K C Q M K A T R R K Y
Sea Urchin Strong. purpuratus XP_781234 487 53968 E443 Q T Q F A F D E D L L T K P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39030 471 53019 K427 Q C I A N F D K C W T D M S V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 91.8 95 N.A. 92.9 65.7 N.A. 70.9 30 30.5 30.2 N.A. 21.1 56.8 29.9 60.9
Protein Similarity: 100 99.7 92.5 96.6 N.A. 95 76 N.A. 80.9 42.8 42.5 43.2 N.A. 28.3 70.7 43.1 74.5
P-Site Identity: 100 100 86.6 66.6 N.A. 73.3 6.6 N.A. 13.3 6.6 6.6 6.6 N.A. 6.6 13.3 0 0
P-Site Similarity: 100 100 86.6 66.6 N.A. 73.3 20 N.A. 26.6 13.3 6.6 6.6 N.A. 13.3 13.3 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 39.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 57.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 7 0 14 0 14 7 0 7 0 0 0 % A
% Cys: 0 7 0 0 0 7 14 7 7 14 7 0 0 0 0 % C
% Asp: 14 0 0 0 0 0 14 0 7 0 0 7 0 0 0 % D
% Glu: 34 0 0 0 0 0 0 7 0 0 34 0 0 34 0 % E
% Phe: 0 14 34 7 0 14 0 0 0 0 0 0 0 0 7 % F
% Gly: 7 47 7 14 0 14 0 14 0 7 0 0 0 14 7 % G
% His: 0 0 0 7 0 0 0 0 0 0 0 14 7 0 0 % H
% Ile: 0 7 7 0 0 7 0 0 0 0 7 7 0 0 0 % I
% Lys: 7 0 0 0 7 0 0 20 14 0 0 0 14 14 0 % K
% Leu: 0 0 0 7 0 0 7 0 20 7 14 0 0 0 14 % L
% Met: 0 0 0 0 0 0 0 14 0 0 0 7 27 0 0 % M
% Asn: 0 0 7 0 7 0 0 0 0 0 7 0 7 0 0 % N
% Pro: 0 0 0 0 34 0 34 0 14 34 0 40 7 20 20 % P
% Gln: 14 0 7 0 0 0 7 0 7 7 0 0 0 0 14 % Q
% Arg: 0 0 0 34 27 0 0 7 20 7 0 7 20 0 0 % R
% Ser: 7 0 20 7 14 47 7 34 0 14 0 0 0 7 7 % S
% Thr: 0 7 0 0 0 0 0 0 0 0 27 7 20 7 20 % T
% Val: 20 14 7 0 0 14 7 0 0 0 7 7 0 7 7 % V
% Trp: 0 0 14 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 14 7 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _