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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
33.03
Human Site:
Y291
Identified Species:
51.9
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
Y291
G
K
L
A
L
P
P
Y
L
T
P
D
A
R
D
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
Y291
G
K
L
A
L
P
P
Y
L
T
P
D
A
R
D
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
Y318
G
K
L
A
L
P
P
Y
L
T
P
D
A
R
D
Dog
Lupus familis
XP_851971
482
53401
Y289
G
K
L
T
L
P
P
Y
L
T
P
D
A
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
Y291
G
K
L
V
L
P
P
Y
L
T
P
D
A
R
D
Rat
Rattus norvegicus
P67999
525
59113
Y315
C
K
L
N
L
P
P
Y
L
T
Q
E
A
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
Y272
C
K
L
N
L
P
P
Y
L
T
Q
E
A
R
D
Chicken
Gallus gallus
P18652
752
84421
F302
A
K
L
G
M
P
Q
F
L
S
A
E
A
Q
S
Frog
Xenopus laevis
P10665
733
82620
F284
A
K
L
G
M
P
Q
F
L
S
N
E
A
Q
S
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
F289
A
K
L
G
M
P
Q
F
L
S
L
E
A
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
E486
I
S
R
R
I
Q
K
E
Q
P
M
I
P
S
S
Honey Bee
Apis mellifera
XP_395876
456
51514
Y293
G
K
L
N
L
P
Q
Y
L
T
P
D
S
R
D
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
F326
A
K
L
S
M
P
H
F
L
T
Q
E
A
Q
S
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
Y296
G
K
L
S
L
P
P
Y
L
T
H
E
A
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
G283
H
V
M
L
T
D
F
G
L
A
K
E
F
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
73.3
N.A.
73.3
33.3
33.3
33.3
N.A.
0
80
40
80
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
80
N.A.
80
66.6
66.6
66.6
N.A.
6.6
86.6
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
0
20
0
0
0
0
0
7
7
0
80
0
0
% A
% Cys:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
40
0
0
60
% D
% Glu:
0
0
0
0
0
0
0
7
0
0
0
54
0
7
7
% E
% Phe:
0
0
0
0
0
0
7
27
0
0
0
0
7
0
0
% F
% Gly:
47
0
0
20
0
0
0
7
0
0
0
0
0
0
7
% G
% His:
7
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
87
0
0
0
0
7
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
87
7
60
0
0
0
94
0
7
0
0
0
0
% L
% Met:
0
0
7
0
27
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
20
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
87
54
0
0
7
40
0
7
0
0
% P
% Gln:
0
0
0
0
0
7
27
0
7
0
20
0
0
27
0
% Q
% Arg:
0
0
7
7
0
0
0
0
0
0
0
0
0
60
0
% R
% Ser:
0
7
0
14
0
0
0
0
0
20
0
0
7
7
27
% S
% Thr:
0
0
0
7
7
0
0
0
0
67
0
0
0
0
0
% T
% Val:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _