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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DKK4
All Species:
12.42
Human Site:
S130
Identified Species:
30.37
UniProt:
Q9UBT3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBT3
NP_055235.1
224
24876
S130
N
Q
P
K
R
K
P
S
I
K
K
S
Q
G
R
Chimpanzee
Pan troglodytes
XP_001144036
224
24908
S130
N
Q
P
K
R
K
P
S
I
K
K
S
Q
G
R
Rhesus Macaque
Macaca mulatta
XP_001097758
224
24836
S130
N
Q
P
K
R
K
P
S
I
K
K
S
Q
G
R
Dog
Lupus familis
XP_848913
218
24461
P127
E
N
K
P
K
R
K
P
N
I
K
S
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ3
221
24242
S130
N
R
P
Q
G
K
P
S
T
K
K
S
Q
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514958
219
24422
N129
N
K
P
R
R
K
S
N
P
N
K
S
Q
G
S
Chicken
Gallus gallus
XP_420494
269
29948
A178
G
W
Q
N
L
G
R
A
Q
S
K
L
S
H
I
Frog
Xenopus laevis
NP_001079319
255
28077
H164
G
W
Q
N
L
G
K
H
H
S
K
I
P
H
I
Zebra Danio
Brachydanio rerio
XP_001339741
277
29604
L186
H
P
R
R
T
T
V
L
S
K
P
Q
Q
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001091929
339
38399
Q149
E
E
E
E
S
I
L
Q
D
T
K
F
K
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.9
78.5
N.A.
75
N.A.
N.A.
71.8
32.3
38
35.3
N.A.
N.A.
N.A.
N.A.
22.4
Protein Similarity:
100
99.5
97.3
86.6
N.A.
83
N.A.
N.A.
79.9
46.4
50.5
44.4
N.A.
N.A.
N.A.
N.A.
34.8
P-Site Identity:
100
100
100
26.6
N.A.
60
N.A.
N.A.
53.3
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
40
N.A.
73.3
N.A.
N.A.
73.3
13.3
6.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
20
10
10
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
20
0
0
0
10
20
0
0
0
0
0
0
0
50
0
% G
% His:
10
0
0
0
0
0
0
10
10
0
0
0
0
20
0
% H
% Ile:
0
0
0
0
0
10
0
0
30
10
0
10
0
0
20
% I
% Lys:
0
10
10
30
10
50
20
0
0
50
90
0
10
0
0
% K
% Leu:
0
0
0
0
20
0
10
10
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
10
0
20
0
0
0
10
10
10
0
0
0
0
0
% N
% Pro:
0
10
50
10
0
0
40
10
10
0
10
0
10
0
0
% P
% Gln:
0
30
20
10
0
0
0
10
10
0
0
10
70
0
10
% Q
% Arg:
0
10
10
20
40
10
10
0
0
0
0
0
0
0
40
% R
% Ser:
0
0
0
0
10
0
10
40
10
20
0
60
10
10
30
% S
% Thr:
0
0
0
0
10
10
0
0
10
10
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _