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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLK
All Species:
35.15
Human Site:
S178
Identified Species:
64.44
UniProt:
Q9UBT6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBT6
NP_057302.1
870
98809
S178
F
D
K
Y
R
A
V
S
K
E
V
K
E
I
L
Chimpanzee
Pan troglodytes
XP_001149102
871
98970
S178
F
D
K
Y
R
A
V
S
K
E
V
K
E
I
L
Rhesus Macaque
Macaca mulatta
XP_001105220
870
98368
S178
F
D
K
Y
R
A
V
S
K
E
V
K
E
I
L
Dog
Lupus familis
XP_536321
861
97742
S178
F
D
K
Y
R
A
V
S
T
E
V
K
E
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUG2
852
95984
S177
F
D
K
Y
R
A
V
S
K
E
V
K
E
I
L
Rat
Rattus norvegicus
NP_612525
851
95088
S177
F
D
K
Y
R
A
V
S
K
E
V
K
E
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512578
873
99083
S178
F
D
K
Y
R
E
V
S
K
E
V
R
E
I
L
Chicken
Gallus gallus
NP_989514
867
97411
S179
F
E
K
Y
R
K
V
S
K
E
V
K
E
I
L
Frog
Xenopus laevis
NP_001086552
862
96259
S179
F
D
K
Y
R
A
V
S
S
E
V
R
E
I
L
Zebra Danio
Brachydanio rerio
XP_691219
888
99434
P134
A
V
E
M
R
D
C
P
E
L
K
D
K
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34409
503
57292
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300273
323
35959
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175420
671
75234
N11
G
E
S
S
S
T
N
N
S
S
R
P
W
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
83.7
N.A.
76.4
73.2
N.A.
66.3
56.9
55.8
48.5
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
100
99.3
97.2
90.1
N.A.
85.6
83.2
N.A.
78.2
70.6
67.9
63.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
86.6
86.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
93.3
93.3
33.3
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
29.2
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
62
0
0
0
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
16
8
0
0
8
0
0
8
70
0
0
70
8
0
% E
% Phe:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% I
% Lys:
0
0
70
0
0
8
0
0
54
0
8
54
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
70
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
77
0
0
0
0
0
8
16
0
0
0
% R
% Ser:
0
0
8
8
8
0
0
70
16
8
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
70
0
0
0
70
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _