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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLK
All Species:
26.36
Human Site:
S249
Identified Species:
48.33
UniProt:
Q9UBT6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBT6
NP_057302.1
870
98809
S249
S
E
H
E
R
S
I
S
P
L
L
F
E
E
S
Chimpanzee
Pan troglodytes
XP_001149102
871
98970
S249
S
E
H
E
R
S
I
S
P
L
L
F
E
E
S
Rhesus Macaque
Macaca mulatta
XP_001105220
870
98368
S249
S
D
H
E
R
S
I
S
P
L
L
F
E
E
S
Dog
Lupus familis
XP_536321
861
97742
S249
R
E
H
E
R
S
I
S
P
L
L
F
D
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUG2
852
95984
S248
T
E
Y
E
R
S
I
S
P
L
L
F
E
D
S
Rat
Rattus norvegicus
NP_612525
851
95088
S248
T
E
R
E
R
S
I
S
P
L
L
F
E
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512578
873
99083
S249
C
E
D
E
L
S
F
S
P
V
L
F
E
D
S
Chicken
Gallus gallus
NP_989514
867
97411
S250
V
N
I
D
G
Y
S
S
S
P
E
L
F
E
D
Frog
Xenopus laevis
NP_001086552
862
96259
F250
E
C
T
S
P
I
L
F
E
D
S
P
S
F
V
Zebra Danio
Brachydanio rerio
XP_691219
888
99434
M206
S
E
Y
D
P
N
F
M
P
M
S
L
D
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34409
503
57292
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300273
323
35959
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175420
671
75234
L81
A
K
L
S
S
L
D
L
S
N
Y
Q
K
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
83.7
N.A.
76.4
73.2
N.A.
66.3
56.9
55.8
48.5
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
100
99.3
97.2
90.1
N.A.
85.6
83.2
N.A.
78.2
70.6
67.9
63.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
60
13.3
0
26.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
73.3
20
6.6
66.6
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
29.2
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
16
0
0
8
0
0
8
0
0
16
31
8
% D
% Glu:
8
54
0
54
0
0
0
0
8
0
8
0
47
39
0
% E
% Phe:
0
0
0
0
0
0
16
8
0
0
0
54
8
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
31
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
47
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
8
0
8
8
8
8
0
47
54
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
16
0
0
0
62
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
8
0
47
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
31
0
0
16
8
54
8
62
16
0
16
0
8
0
54
% S
% Thr:
16
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
8
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _