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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLK
All Species:
11.52
Human Site:
S715
Identified Species:
21.11
UniProt:
Q9UBT6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBT6
NP_057302.1
870
98809
S715
D
N
S
S
K
A
E
S
I
D
A
L
S
N
K
Chimpanzee
Pan troglodytes
XP_001149102
871
98970
S715
D
N
S
S
K
A
E
S
I
D
A
L
S
N
K
Rhesus Macaque
Macaca mulatta
XP_001105220
870
98368
S715
D
N
S
S
K
A
E
S
I
D
A
L
S
N
K
Dog
Lupus familis
XP_536321
861
97742
K710
E
T
E
D
N
P
A
K
A
E
S
V
D
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUG2
852
95984
G700
V
D
G
V
D
L
T
G
T
E
D
R
S
L
K
Rat
Rattus norvegicus
NP_612525
851
95088
T699
D
G
A
D
L
T
E
T
E
D
R
S
P
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512578
873
99083
K715
V
E
M
H
S
R
W
K
H
V
E
S
F
S
K
Chicken
Gallus gallus
NP_989514
867
97411
V708
D
K
K
F
T
Q
I
V
S
E
K
P
H
R
E
Frog
Xenopus laevis
NP_001086552
862
96259
Q705
N
T
E
T
T
T
V
Q
H
V
E
L
H
I
N
Zebra Danio
Brachydanio rerio
XP_691219
888
99434
A704
T
S
T
S
E
P
M
A
D
G
D
D
G
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34409
503
57292
S353
P
L
C
F
T
P
L
S
Q
E
S
F
L
R
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300273
323
35959
E173
F
M
A
A
S
L
D
E
A
H
L
D
I
T
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175420
671
75234
I521
Q
I
D
S
G
K
V
I
P
N
Q
E
C
M
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
83.7
N.A.
76.4
73.2
N.A.
66.3
56.9
55.8
48.5
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
100
99.3
97.2
90.1
N.A.
85.6
83.2
N.A.
78.2
70.6
67.9
63.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
100
0
N.A.
13.3
20
N.A.
6.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
33.3
N.A.
13.3
20
20
40
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
29.2
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
24
8
8
16
0
24
0
0
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
39
8
8
16
8
0
8
0
8
31
16
16
8
0
8
% D
% Glu:
8
8
16
0
8
0
31
8
8
31
16
8
0
0
16
% E
% Phe:
8
0
0
16
0
0
0
0
0
0
0
8
8
0
0
% F
% Gly:
0
8
8
0
8
0
0
8
0
8
0
0
8
0
0
% G
% His:
0
0
0
8
0
0
0
0
16
8
0
0
16
0
0
% H
% Ile:
0
8
0
0
0
0
8
8
24
0
0
0
8
8
0
% I
% Lys:
0
8
8
0
24
8
0
16
0
0
8
0
0
8
47
% K
% Leu:
0
8
0
0
8
16
8
0
0
0
8
31
8
8
8
% L
% Met:
0
8
8
0
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
8
24
0
0
8
0
0
0
0
8
0
0
0
31
8
% N
% Pro:
8
0
0
0
0
24
0
0
8
0
0
8
8
0
0
% P
% Gln:
8
0
0
0
0
8
0
8
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
8
8
0
16
0
% R
% Ser:
0
8
24
39
16
0
0
31
8
0
16
16
31
8
0
% S
% Thr:
8
16
8
8
24
16
8
8
8
0
0
0
0
8
8
% T
% Val:
16
0
0
8
0
0
16
8
0
16
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _