KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLK
All Species:
28.79
Human Site:
S851
Identified Species:
52.78
UniProt:
Q9UBT6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBT6
NP_057302.1
870
98809
S851
P
G
L
M
T
K
Y
S
T
S
K
K
I
K
P
Chimpanzee
Pan troglodytes
XP_001149102
871
98970
S852
P
G
L
M
T
K
Y
S
T
S
K
K
I
K
P
Rhesus Macaque
Macaca mulatta
XP_001105220
870
98368
S852
P
G
L
M
T
K
Y
S
S
K
K
I
K
P
N
Dog
Lupus familis
XP_536321
861
97742
S842
P
G
L
M
T
K
Y
S
A
S
K
K
T
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUG2
852
95984
S833
P
G
T
K
T
K
S
S
T
L
K
K
T
K
P
Rat
Rattus norvegicus
NP_612525
851
95088
S832
A
G
R
K
T
K
G
S
T
S
K
R
T
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512578
873
99083
S854
P
G
V
L
T
Q
H
S
S
S
K
K
T
K
P
Chicken
Gallus gallus
NP_989514
867
97411
S848
S
G
L
T
T
S
Q
S
A
S
K
K
A
K
S
Frog
Xenopus laevis
NP_001086552
862
96259
P843
P
A
A
T
N
Q
N
P
A
S
K
K
S
K
P
Zebra Danio
Brachydanio rerio
XP_691219
888
99434
T850
L
I
L
L
Q
I
H
T
D
H
I
Q
K
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34409
503
57292
T485
D
E
K
K
R
S
K
T
I
T
E
F
W
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300273
323
35959
T305
V
G
L
G
I
G
K
T
D
T
P
Q
V
R
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175420
671
75234
P653
K
D
S
S
K
H
I
P
I
H
A
F
F
T
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
83.7
N.A.
76.4
73.2
N.A.
66.3
56.9
55.8
48.5
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
100
99.3
97.2
90.1
N.A.
85.6
83.2
N.A.
78.2
70.6
67.9
63.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
60
86.6
N.A.
66.6
60
N.A.
60
53.3
40
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
66.6
86.6
N.A.
66.6
66.6
N.A.
93.3
53.3
46.6
33.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
29.2
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
0
0
24
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
16
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
16
8
0
0
% F
% Gly:
0
70
0
8
0
8
8
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
8
16
0
0
16
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
8
8
0
16
0
8
8
16
8
0
% I
% Lys:
8
0
8
24
8
47
16
0
0
8
70
54
16
62
8
% K
% Leu:
8
0
54
16
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
8
% N
% Pro:
54
0
0
0
0
0
0
16
0
0
8
0
0
8
54
% P
% Gln:
0
0
0
0
8
16
8
0
0
0
0
16
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
8
0
8
8
0
16
8
62
16
54
0
0
8
0
16
% S
% Thr:
0
0
8
16
62
0
0
24
31
16
0
0
31
8
0
% T
% Val:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _