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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLK
All Species:
29.09
Human Site:
Y221
Identified Species:
53.33
UniProt:
Q9UBT6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBT6
NP_057302.1
870
98809
Y221
W
P
E
D
K
R
R
Y
F
I
K
M
G
S
S
Chimpanzee
Pan troglodytes
XP_001149102
871
98970
Y221
W
P
E
D
K
R
R
Y
F
I
K
M
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001105220
870
98368
Y221
W
P
E
D
K
R
K
Y
F
I
K
M
G
N
S
Dog
Lupus familis
XP_536321
861
97742
Y221
W
P
E
D
K
R
K
Y
F
I
K
T
G
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUG2
852
95984
Y220
W
P
E
D
K
R
R
Y
F
I
K
M
G
N
Y
Rat
Rattus norvegicus
NP_612525
851
95088
Y220
W
P
E
D
K
R
R
Y
F
I
K
M
G
N
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512578
873
99083
Y221
W
P
E
D
K
R
R
Y
F
F
K
A
G
N
T
Chicken
Gallus gallus
NP_989514
867
97411
Y222
W
P
E
D
K
R
R
Y
F
L
N
T
E
N
T
Frog
Xenopus laevis
NP_001086552
862
96259
F222
W
T
E
D
K
R
T
F
I
I
G
A
E
N
S
Zebra Danio
Brachydanio rerio
XP_691219
888
99434
V178
K
K
L
C
P
D
L
V
I
V
P
T
N
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34409
503
57292
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300273
323
35959
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175420
671
75234
Q53
S
K
G
S
K
Y
F
Q
N
E
E
R
K
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.9
83.7
N.A.
76.4
73.2
N.A.
66.3
56.9
55.8
48.5
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
100
99.3
97.2
90.1
N.A.
85.6
83.2
N.A.
78.2
70.6
67.9
63.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
86.6
73.3
N.A.
86.6
86.6
N.A.
73.3
60
46.6
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
86.6
80
60
6.6
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
20.9
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
29.2
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
70
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
70
0
0
0
0
0
0
8
8
0
16
8
0
% E
% Phe:
0
0
0
0
0
0
8
8
62
8
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
54
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
16
54
0
0
0
0
0
% I
% Lys:
8
16
0
0
77
0
16
0
0
0
54
0
8
0
0
% K
% Leu:
0
0
8
0
0
0
8
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
0
8
54
0
% N
% Pro:
0
62
0
0
8
0
0
0
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
70
47
0
0
0
0
8
0
0
0
% R
% Ser:
8
0
0
8
0
0
0
0
0
0
0
0
0
16
31
% S
% Thr:
0
8
0
0
0
0
8
0
0
0
0
24
0
0
16
% T
% Val:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
62
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _