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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DBF4 All Species: 16.06
Human Site: S525 Identified Species: 44.17
UniProt: Q9UBU7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBU7 NP_006707.1 674 76858 S525 L K E K D L H S I F T H D S G
Chimpanzee Pan troglodytes XP_528041 673 76850 S524 L K E K D L H S I F T H D S G
Rhesus Macaque Macaca mulatta XP_001104753 669 76400 S520 L K E K D L H S I F T H D S G
Dog Lupus familis XP_532451 679 77542 S527 L K E K D L H S I F G H D S G
Cat Felis silvestris
Mouse Mus musculus Q9QZ41 663 74157 L526 H A S D L V A L N T S K E Q L
Rat Rattus norvegicus XP_231388 666 74806 T528 G H D S E L V T L N S S R E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418638 708 79807 P556 L K K T D A N P T F V E K H R
Frog Xenopus laevis Q7ZZH7 661 73680 P525 A D A N I K L P K T V N D L H
Zebra Danio Brachydanio rerio NP_001128607 612 69278 T478 R T E Q Q N R T N P D V H P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.6 82.1 N.A. 66.3 67.6 N.A. N.A. 47.4 32.7 28.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 97 90.2 N.A. 77.7 80.1 N.A. N.A. 63.2 51.7 47.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 0 6.6 N.A. N.A. 26.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 20 40 N.A. N.A. 40 13.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 12 0 0 12 12 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 12 12 56 0 0 0 0 0 12 0 56 0 0 % D
% Glu: 0 0 56 0 12 0 0 0 0 0 0 12 12 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 56 0 0 0 0 0 % F
% Gly: 12 0 0 0 0 0 0 0 0 0 12 0 0 0 45 % G
% His: 12 12 0 0 0 0 45 0 0 0 0 45 12 12 12 % H
% Ile: 0 0 0 0 12 0 0 0 45 0 0 0 0 0 0 % I
% Lys: 0 56 12 45 0 12 0 0 12 0 0 12 12 0 0 % K
% Leu: 56 0 0 0 12 56 12 12 12 0 0 0 0 12 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 12 0 12 12 0 23 12 0 12 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 23 0 12 0 0 0 12 0 % P
% Gln: 0 0 0 12 12 0 0 0 0 0 0 0 0 12 12 % Q
% Arg: 12 0 0 0 0 0 12 0 0 0 0 0 12 0 12 % R
% Ser: 0 0 12 12 0 0 0 45 0 0 23 12 0 45 0 % S
% Thr: 0 12 0 12 0 0 0 23 12 23 34 0 0 0 0 % T
% Val: 0 0 0 0 0 12 12 0 0 0 23 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _