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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS7A
All Species:
30.61
Human Site:
S193
Identified Species:
48.1
UniProt:
Q9UBW8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBW8
NP_001157565.1
275
30277
S193
S
G
I
E
E
Q
V
S
R
A
N
Q
H
K
E
Chimpanzee
Pan troglodytes
XP_001162737
248
27299
I170
Q
R
Q
D
L
S
A
I
A
R
T
L
Q
E
W
Rhesus Macaque
Macaca mulatta
XP_001108537
275
30301
S193
S
G
I
E
E
Q
V
S
R
A
N
Q
H
K
E
Dog
Lupus familis
XP_543849
275
30288
S193
S
G
I
E
E
Q
V
S
R
A
N
Q
H
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ04
275
30206
S193
S
G
I
E
E
Q
V
S
R
A
N
Q
H
K
E
Rat
Rattus norvegicus
NP_001157563
275
30201
S193
S
G
I
E
E
Q
V
S
R
A
N
L
H
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518093
661
70489
S395
A
G
I
E
E
Q
V
S
R
A
N
Q
H
K
E
Chicken
Gallus gallus
NP_001025946
275
30386
S193
S
G
I
E
E
Q
V
S
R
A
N
Q
H
K
E
Frog
Xenopus laevis
NP_001089653
264
29433
V184
W
C
D
G
C
E
A
V
L
V
G
I
E
Q
Q
Zebra Danio
Brachydanio rerio
XP_697089
266
29243
N183
E
E
Q
V
S
R
A
N
Q
Y
R
E
S
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4S8
278
31049
N194
N
S
C
D
S
V
S
N
C
I
E
M
Q
I
K
Honey Bee
Apis mellifera
XP_395310
282
30757
T197
A
C
I
E
E
Q
V
T
R
A
N
V
E
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785591
270
30197
E191
T
M
L
N
N
V
E
E
Q
I
H
R
A
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JU3
260
29450
E182
S
N
W
L
N
T
S
E
N
L
L
I
S
I
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGS1
417
44522
A214
Q
E
L
E
A
T
M
A
N
L
R
D
E
A
D
Conservation
Percent
Protein Identity:
100
87.6
99.2
99.6
N.A.
98.9
98.9
N.A.
36.7
88.7
57
52
N.A.
40.6
43.6
N.A.
51.2
Protein Similarity:
100
88.3
100
99.6
N.A.
99.6
99.6
N.A.
39.7
94.5
76.3
68.3
N.A.
58.6
60.9
N.A.
70.1
P-Site Identity:
100
0
100
100
N.A.
100
93.3
N.A.
93.3
100
0
0
N.A.
0
60
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
93.3
N.A.
100
100
20
33.3
N.A.
26.6
80
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.8
N.A.
24.9
Protein Similarity:
N.A.
N.A.
N.A.
50.1
N.A.
40.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
7
0
20
7
7
54
0
0
7
7
0
% A
% Cys:
0
14
7
0
7
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
14
0
0
0
0
0
0
0
7
0
0
7
% D
% Glu:
7
14
0
60
54
7
7
14
0
0
7
7
20
7
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
47
0
7
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
47
0
0
% H
% Ile:
0
0
54
0
0
0
0
7
0
14
0
14
0
14
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
14
% K
% Leu:
0
0
14
7
7
0
0
0
7
14
7
14
0
0
7
% L
% Met:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% M
% Asn:
7
7
0
7
14
0
0
14
14
0
54
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
14
0
0
54
0
0
14
0
0
40
14
14
20
% Q
% Arg:
0
7
0
0
0
7
0
0
54
7
14
7
0
0
0
% R
% Ser:
47
7
0
0
14
7
14
47
0
0
0
0
14
0
0
% S
% Thr:
7
0
0
0
0
14
0
7
0
0
7
0
0
0
0
% T
% Val:
0
0
0
7
0
14
54
7
0
7
0
7
0
0
0
% V
% Trp:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _