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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS7A
All Species:
23.64
Human Site:
T240
Identified Species:
37.14
UniProt:
Q9UBW8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBW8
NP_001157565.1
275
30277
T240
Q
D
P
E
Q
H
L
T
E
L
R
E
P
A
P
Chimpanzee
Pan troglodytes
XP_001162737
248
27299
A214
Q
Q
I
E
S
E
V
A
N
L
K
K
T
I
K
Rhesus Macaque
Macaca mulatta
XP_001108537
275
30301
T240
Q
D
P
E
Q
H
L
T
E
L
R
E
P
A
P
Dog
Lupus familis
XP_543849
275
30288
T240
Q
D
P
E
Q
H
L
T
E
L
R
E
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ04
275
30206
T240
Q
D
P
E
Q
H
L
T
E
L
R
E
P
A
S
Rat
Rattus norvegicus
NP_001157563
275
30201
T240
Q
D
P
E
Q
H
L
T
E
L
R
E
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518093
661
70489
Q466
D
I
L
E
M
T
V
Q
H
L
Q
R
L
H
R
Chicken
Gallus gallus
NP_001025946
275
30386
T240
Q
D
P
E
Q
H
L
T
E
L
R
E
P
A
P
Frog
Xenopus laevis
NP_001089653
264
29433
D230
T
A
S
S
S
A
Q
D
T
D
Q
H
L
A
E
Zebra Danio
Brachydanio rerio
XP_697089
266
29243
Q227
P
A
G
A
A
S
N
Q
D
A
D
Q
P
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4S8
278
31049
T243
D
E
S
M
Q
I
D
T
H
G
P
G
T
S
G
Honey Bee
Apis mellifera
XP_395310
282
30757
G244
D
M
A
G
G
S
S
G
S
G
G
S
E
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785591
270
30197
M235
Q
E
G
D
E
A
D
M
G
V
D
T
R
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JU3
260
29450
V226
S
L
S
M
K
G
D
V
D
I
R
G
N
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGS1
417
44522
H316
R
Q
Q
Q
N
H
H
H
H
H
Q
S
N
Q
S
Conservation
Percent
Protein Identity:
100
87.6
99.2
99.6
N.A.
98.9
98.9
N.A.
36.7
88.7
57
52
N.A.
40.6
43.6
N.A.
51.2
Protein Similarity:
100
88.3
100
99.6
N.A.
99.6
99.6
N.A.
39.7
94.5
76.3
68.3
N.A.
58.6
60.9
N.A.
70.1
P-Site Identity:
100
20
100
100
N.A.
93.3
100
N.A.
13.3
100
6.6
13.3
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
40
100
100
N.A.
93.3
100
N.A.
26.6
100
13.3
26.6
N.A.
26.6
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.8
N.A.
24.9
Protein Similarity:
N.A.
N.A.
N.A.
50.1
N.A.
40.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
7
7
14
0
7
0
7
0
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
40
0
7
0
0
20
7
14
7
14
0
0
0
0
% D
% Glu:
0
14
0
54
7
7
0
0
40
0
0
40
7
7
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
14
7
7
7
0
7
7
14
7
14
0
0
7
% G
% His:
0
0
0
0
0
47
7
7
20
7
0
7
0
7
0
% H
% Ile:
0
7
7
0
0
7
0
0
0
7
0
0
0
7
0
% I
% Lys:
0
0
0
0
7
0
0
0
0
0
7
7
0
7
7
% K
% Leu:
0
7
7
0
0
0
40
0
0
54
0
0
14
0
0
% L
% Met:
0
7
0
14
7
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
7
0
7
0
7
0
0
0
14
0
0
% N
% Pro:
7
0
40
0
0
0
0
0
0
0
7
0
47
0
34
% P
% Gln:
54
14
7
7
47
0
7
14
0
0
20
7
0
7
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
47
7
7
0
7
% R
% Ser:
7
0
20
7
14
14
7
0
7
0
0
14
0
14
20
% S
% Thr:
7
0
0
0
0
7
0
47
7
0
0
7
14
0
0
% T
% Val:
0
0
0
0
0
0
14
7
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _