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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS7A
All Species:
25.15
Human Site:
T249
Identified Species:
39.52
UniProt:
Q9UBW8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBW8
NP_001157565.1
275
30277
T249
L
R
E
P
A
P
G
T
N
Q
R
Q
P
S
K
Chimpanzee
Pan troglodytes
XP_001162737
248
27299
T223
L
K
K
T
I
K
V
T
T
A
A
A
A
A
A
Rhesus Macaque
Macaca mulatta
XP_001108537
275
30301
T249
L
R
E
P
A
P
G
T
N
Q
R
Q
P
S
K
Dog
Lupus familis
XP_543849
275
30288
T249
L
R
E
P
A
P
G
T
N
Q
R
Q
P
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ04
275
30206
T249
L
R
E
P
A
S
G
T
N
Q
R
Q
P
S
K
Rat
Rattus norvegicus
NP_001157563
275
30201
T249
L
R
E
P
A
P
G
T
N
Q
R
Q
P
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518093
661
70489
G475
L
Q
R
L
H
R
G
G
T
R
R
D
R
A
P
Chicken
Gallus gallus
NP_001025946
275
30386
T249
L
R
E
P
A
P
G
T
N
Q
R
Q
T
S
K
Frog
Xenopus laevis
NP_001089653
264
29433
E239
D
Q
H
L
A
E
R
E
G
P
P
L
T
E
Q
Zebra Danio
Brachydanio rerio
XP_697089
266
29243
R236
A
D
Q
P
A
E
P
R
D
P
A
S
S
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4S8
278
31049
L252
G
P
G
T
S
G
G
L
G
Q
S
E
L
R
K
Honey Bee
Apis mellifera
XP_395310
282
30757
E253
G
G
S
E
S
S
R
E
A
L
S
A
P
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785591
270
30197
A244
V
D
T
R
E
M
E
A
Q
S
M
K
P
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JU3
260
29450
F235
I
R
G
N
K
E
M
F
G
E
P
S
G
V
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGS1
417
44522
T325
H
Q
S
N
Q
S
G
T
N
S
L
L
T
S
G
Conservation
Percent
Protein Identity:
100
87.6
99.2
99.6
N.A.
98.9
98.9
N.A.
36.7
88.7
57
52
N.A.
40.6
43.6
N.A.
51.2
Protein Similarity:
100
88.3
100
99.6
N.A.
99.6
99.6
N.A.
39.7
94.5
76.3
68.3
N.A.
58.6
60.9
N.A.
70.1
P-Site Identity:
100
13.3
100
100
N.A.
93.3
100
N.A.
20
93.3
6.6
13.3
N.A.
20
6.6
N.A.
20
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
100
N.A.
40
93.3
20
33.3
N.A.
33.3
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.8
N.A.
24.9
Protein Similarity:
N.A.
N.A.
N.A.
50.1
N.A.
40.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
54
0
0
7
7
7
14
14
7
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
0
0
0
0
0
0
7
0
0
7
0
0
7
% D
% Glu:
0
0
40
7
7
20
7
14
0
7
0
7
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
14
7
14
0
0
7
60
7
20
0
0
0
7
0
7
% G
% His:
7
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
7
0
7
7
0
0
0
0
0
7
0
0
54
% K
% Leu:
54
0
0
14
0
0
0
7
0
7
7
14
7
0
0
% L
% Met:
0
0
0
0
0
7
7
0
0
0
7
0
0
0
7
% M
% Asn:
0
0
0
14
0
0
0
0
47
0
0
0
0
0
0
% N
% Pro:
0
7
0
47
0
34
7
0
0
14
14
0
47
7
7
% P
% Gln:
0
20
7
0
7
0
0
0
7
47
0
40
0
7
7
% Q
% Arg:
0
47
7
7
0
7
14
7
0
7
47
0
7
7
0
% R
% Ser:
0
0
14
0
14
20
0
0
0
14
14
14
7
54
0
% S
% Thr:
0
0
7
14
0
0
0
54
14
0
0
0
20
0
0
% T
% Val:
7
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _