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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A2 All Species: 17.88
Human Site: S745 Identified Species: 32.78
UniProt: Q9UBY0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBY0 NP_003039.2 812 91520 S745 D S G R D M P S T P P T P H S
Chimpanzee Pan troglodytes XP_525838 812 91515 S745 D S G R D M P S T P P T P H S
Rhesus Macaque Macaca mulatta XP_001108368 812 91659 S745 E S G R E K P S T P S T P H S
Dog Lupus familis XP_531775 801 90567 C734 D L G Q G Q P C T P A A P H S
Cat Felis silvestris
Mouse Mus musculus Q8BUE1 797 90919 T732 S F S Y R S N T S W E D Q A G
Rat Rattus norvegicus P48763 813 91384 S745 G S A R A P P S V T P A P R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514675 940 104115 S873 D A G R G Q P S D A P S P R G
Chicken Gallus gallus Q5ZJ75 574 64115 A509 L T E G E Y E A Q Y I K R Q D
Frog Xenopus laevis NP_001081553 781 87800 T712 A S P E S V D T V N E T Q E E
Zebra Danio Brachydanio rerio NP_001107567 746 85353 M681 D N E P N E E M P N K M S H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P35449 667 75263 R602 R K L H E M N R P S V Q I T D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 T470 T S Y D D E D T P P G S G F R
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 T568 G L N E T E N T S P N P A R S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 96.5 87.1 N.A. 52.9 90.9 N.A. 71.6 21.7 44.8 45.2 N.A. N.A. N.A. 34.8 N.A.
Protein Similarity: 100 99.7 97.6 90.7 N.A. 68.7 94.2 N.A. 77.5 38.9 62.5 63.5 N.A. N.A. N.A. 53.6 N.A.
P-Site Identity: 100 100 73.3 53.3 N.A. 0 46.6 N.A. 46.6 0 13.3 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 86.6 60 N.A. 13.3 46.6 N.A. 60 20 26.6 26.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.6 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 38.9 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 8 0 0 8 0 8 8 16 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 39 0 0 8 24 0 16 0 8 0 0 8 0 0 16 % D
% Glu: 8 0 16 16 24 24 16 0 0 0 16 0 0 8 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 16 0 39 8 16 0 0 0 0 0 8 0 8 0 16 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 39 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % I
% Lys: 0 8 0 0 0 8 0 0 0 0 8 8 0 0 0 % K
% Leu: 8 16 8 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 24 0 8 0 0 0 8 0 0 0 % M
% Asn: 0 8 8 0 8 0 24 0 0 16 8 0 0 0 0 % N
% Pro: 0 0 8 8 0 8 47 0 24 47 31 8 47 0 8 % P
% Gln: 0 0 0 8 0 16 0 0 8 0 0 8 16 8 0 % Q
% Arg: 8 0 0 39 8 0 0 8 0 0 0 0 8 24 8 % R
% Ser: 8 47 8 0 8 8 0 39 16 8 8 16 8 0 47 % S
% Thr: 8 8 0 0 8 0 0 31 31 8 0 31 0 8 0 % T
% Val: 0 0 0 0 0 8 0 0 16 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 8 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _