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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC9A2 All Species: 27.88
Human Site: Y346 Identified Species: 51.11
UniProt: Q9UBY0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBY0 NP_003039.2 812 91520 Y346 C A M T M N K Y V E E N V S Q
Chimpanzee Pan troglodytes XP_525838 812 91515 Y346 C A M T M N K Y V E E N V S Q
Rhesus Macaque Macaca mulatta XP_001108368 812 91659 Y346 C A M T M N K Y V E E N V S Q
Dog Lupus familis XP_531775 801 90567 Y335 C A M T M N K Y V E E N V S Q
Cat Felis silvestris
Mouse Mus musculus Q8BUE1 797 90919 Y338 C A V T M K K Y V E E N V S Q
Rat Rattus norvegicus P48763 813 91384 Y347 C A M T M N K Y V E E N V S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514675 940 104115 Y474 C A M T M N K Y V E E N V S Q
Chicken Gallus gallus Q5ZJ75 574 64115 H136 F E S G Y S L H K G N F F Q N
Frog Xenopus laevis NP_001081553 781 87800 S332 S A E L F H L S G I M A L I A
Zebra Danio Brachydanio rerio NP_001107567 746 85353 H307 R S C T T I R H V I K M V G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P35449 667 75263 L229 G S E N L S V L D Y A T G G L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWU6 535 59320 P97 F F L F L L P P I I F Q S G F
Baker's Yeast Sacchar. cerevisiae Q04121 633 70130 A195 A D A M S V G A T L S A T D P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 96.5 87.1 N.A. 52.9 90.9 N.A. 71.6 21.7 44.8 45.2 N.A. N.A. N.A. 34.8 N.A.
Protein Similarity: 100 99.7 97.6 90.7 N.A. 68.7 94.2 N.A. 77.5 38.9 62.5 63.5 N.A. N.A. N.A. 53.6 N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 100 N.A. 100 0 6.6 20 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 100 13.3 20 46.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.6 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 38.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 62 8 0 0 0 0 8 0 0 8 16 0 0 8 % A
% Cys: 54 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 8 0 0 0 0 8 0 % D
% Glu: 0 8 16 0 0 0 0 0 0 54 54 0 0 0 0 % E
% Phe: 16 8 0 8 8 0 0 0 0 0 8 8 8 0 8 % F
% Gly: 8 0 0 8 0 0 8 0 8 8 0 0 8 24 0 % G
% His: 0 0 0 0 0 8 0 16 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 8 24 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 8 54 0 8 0 8 0 0 0 0 % K
% Leu: 0 0 8 8 16 8 16 8 0 8 0 0 8 0 8 % L
% Met: 0 0 47 8 54 0 0 0 0 0 8 8 0 0 0 % M
% Asn: 0 0 0 8 0 47 0 0 0 0 8 54 0 0 8 % N
% Pro: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 54 % Q
% Arg: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 8 16 8 0 8 16 0 8 0 0 8 0 8 54 8 % S
% Thr: 0 0 0 62 8 0 0 0 8 0 0 8 8 0 0 % T
% Val: 0 0 8 0 0 8 8 0 62 0 0 0 62 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 54 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _