KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APEX2
All Species:
6.36
Human Site:
S227
Identified Species:
17.5
UniProt:
Q9UBZ4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBZ4
NP_055296.2
518
57401
S227
P
G
R
K
W
M
D
S
L
L
S
N
L
G
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092143
518
57312
S227
P
G
R
K
W
M
D
S
L
L
S
N
L
G
C
Dog
Lupus familis
XP_548620
487
54088
D198
D
P
G
R
K
W
M
D
G
L
L
S
N
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q68G58
516
57321
G226
P
G
R
K
W
M
D
G
L
L
S
N
P
G
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510545
549
60839
G246
W
E
P
G
K
A
P
G
K
G
E
V
A
D
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086779
517
57708
K223
G
D
P
I
P
S
Q
K
G
D
S
E
T
V
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784420
596
66588
D256
D
E
E
R
H
V
H
D
D
S
N
I
D
V
E
Poplar Tree
Populus trichocarpa
XP_002304326
617
69328
T242
P
D
R
R
E
A
Y
T
C
W
S
S
S
T
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38207
520
59427
I230
V
N
V
C
R
D
L
I
D
S
A
D
T
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
81.4
N.A.
79.5
N.A.
N.A.
48
N.A.
52.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.7
Protein Similarity:
100
N.A.
98.4
87.2
N.A.
86.2
N.A.
N.A.
63.3
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
55.3
P-Site Identity:
100
N.A.
100
6.6
N.A.
80
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
100
20
N.A.
80
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
41.9
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
23
0
0
0
0
12
0
12
0
0
% A
% Cys:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
23
% C
% Asp:
23
23
0
0
0
12
34
23
23
12
0
12
12
12
12
% D
% Glu:
0
23
12
0
12
0
0
0
0
0
12
12
0
0
23
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
34
12
12
0
0
0
23
23
12
0
0
0
34
23
% G
% His:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
12
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
34
23
0
0
12
12
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
12
0
34
45
12
0
23
23
0
% L
% Met:
0
0
0
0
0
34
12
0
0
0
0
0
0
0
12
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
12
34
12
0
0
% N
% Pro:
45
12
23
0
12
0
12
0
0
0
0
0
12
0
12
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
45
34
12
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
0
23
0
23
56
23
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
23
12
0
% T
% Val:
12
0
12
0
0
12
0
0
0
0
0
12
0
23
0
% V
% Trp:
12
0
0
0
34
12
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _