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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APEX2
All Species:
5.76
Human Site:
S386
Identified Species:
15.83
UniProt:
Q9UBZ4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBZ4
NP_055296.2
518
57401
S386
P
Q
P
S
Q
V
G
S
S
R
G
Q
K
N
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092143
518
57312
S386
P
R
P
S
Q
A
G
S
G
R
G
Q
K
N
L
Dog
Lupus familis
XP_548620
487
54088
G357
R
L
R
P
N
Q
T
G
S
S
R
G
Q
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q68G58
516
57321
P385
L
R
K
S
Q
G
G
P
K
R
K
Q
K
N
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510545
549
60839
V405
N
S
A
E
K
T
K
V
G
V
K
K
N
R
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086779
517
57708
T382
P
S
D
K
L
N
S
T
S
K
K
K
S
K
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784420
596
66588
G415
Q
S
L
V
G
K
P
G
K
R
A
K
T
D
G
Poplar Tree
Populus trichocarpa
XP_002304326
617
69328
R401
F
N
E
C
S
V
S
R
P
S
T
S
P
S
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38207
520
59427
R389
A
R
Y
K
Y
N
L
R
N
H
N
V
L
E
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
81.4
N.A.
79.5
N.A.
N.A.
48
N.A.
52.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.7
Protein Similarity:
100
N.A.
98.4
87.2
N.A.
86.2
N.A.
N.A.
63.3
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
55.3
P-Site Identity:
100
N.A.
80
6.6
N.A.
53.3
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
86.6
13.3
N.A.
60
N.A.
N.A.
13.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
41.9
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
12
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
12
12
0
0
0
0
0
0
0
0
0
12
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
12
34
23
23
0
23
12
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
12
23
12
12
12
0
23
12
34
34
34
23
0
% K
% Leu:
12
12
12
0
12
0
12
0
0
0
0
0
12
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
12
12
0
0
12
23
0
0
12
0
12
0
12
34
0
% N
% Pro:
34
0
23
12
0
0
12
12
12
0
0
0
12
0
0
% P
% Gln:
12
12
0
0
34
12
0
0
0
0
0
34
12
0
0
% Q
% Arg:
12
34
12
0
0
0
0
23
0
45
12
0
0
12
0
% R
% Ser:
0
34
0
34
12
0
23
23
34
23
0
12
12
12
12
% S
% Thr:
0
0
0
0
0
12
12
12
0
0
12
0
12
0
12
% T
% Val:
0
0
0
12
0
23
0
12
0
12
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _