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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APEX2
All Species:
15.45
Human Site:
T503
Identified Species:
42.5
UniProt:
Q9UBZ4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBZ4
NP_055296.2
518
57401
T503
A
R
P
R
G
P
P
T
D
P
S
S
R
C
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092143
518
57312
T503
A
R
P
R
G
P
P
T
D
P
S
S
R
C
N
Dog
Lupus familis
XP_548620
487
54088
D473
R
P
R
G
P
P
T
D
P
S
S
R
C
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q68G58
516
57321
S501
A
R
P
R
G
P
P
S
D
P
S
S
R
C
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510545
549
60839
T529
A
R
P
V
G
H
A
T
N
P
A
A
R
C
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086779
517
57708
N498
R
P
E
G
H
S
S
N
P
Q
A
R
C
N
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784420
596
66588
N575
K
R
P
E
G
H
K
N
N
P
E
A
R
C
N
Poplar Tree
Populus trichocarpa
XP_002304326
617
69328
S598
S
R
A
E
G
P
V
S
N
P
E
A
N
C
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38207
520
59427
G505
W
I
C
K
R
S
R
G
D
S
N
N
T
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.1
81.4
N.A.
79.5
N.A.
N.A.
48
N.A.
52.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.7
Protein Similarity:
100
N.A.
98.4
87.2
N.A.
86.2
N.A.
N.A.
63.3
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
N.A.
55.3
P-Site Identity:
100
N.A.
100
13.3
N.A.
93.3
N.A.
N.A.
53.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
N.A.
100
13.3
N.A.
100
N.A.
N.A.
80
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
41.9
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
33.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
12
0
0
0
12
0
0
0
23
34
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
23
67
0
% C
% Asp:
0
0
0
0
0
0
0
12
45
0
0
0
0
0
12
% D
% Glu:
0
0
12
23
0
0
0
0
0
0
23
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% F
% Gly:
0
0
0
23
67
0
0
12
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
12
23
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
23
34
0
12
12
12
23
45
% N
% Pro:
0
23
56
0
12
56
34
0
23
67
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
23
67
12
34
12
0
12
0
0
0
0
23
56
0
0
% R
% Ser:
12
0
0
0
0
23
12
23
0
23
45
34
0
0
12
% S
% Thr:
0
0
0
0
0
0
12
34
0
0
0
0
12
0
0
% T
% Val:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _