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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKX1-2 All Species: 0
Human Site: S14 Identified Species: 0
UniProt: Q9UD57 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UD57 XP_002343058.1 332 34708 S14 G G A K A A P S H H K I S F S
Chimpanzee Pan troglodytes XP_521630 398 41798 P37 H R A R G G F P E P R Q A A A
Rhesus Macaque Macaca mulatta Q2VL87 297 30903
Dog Lupus familis XP_544059 354 36219 P17 G A A A Q P Q P Q A S P S A A
Cat Felis silvestris
Mouse Mus musculus P42580 305 31994
Rat Rattus norvegicus P63156 327 35117 A21 S H R A G S P A L P K G D P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P19601 232 25205
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q98876 276 29946
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera P15858 74 8968
Nematode Worm Caenorhab. elegans P53547 132 14911
Sea Urchin Strong. purpuratus NP_001009577 432 47583 P123 Q E Q S P T R P P K L T P F S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.3 26.5 60.1 N.A. 69.8 26.5 N.A. N.A. 38.8 N.A. 22.8 N.A. N.A. 20.1 20.4 29.8
Protein Similarity: 100 71.1 34.9 65.8 N.A. 75.3 35.8 N.A. N.A. 43 N.A. 35.8 N.A. N.A. 21.3 23.7 40.5
P-Site Identity: 100 6.6 0 20 N.A. 0 13.3 N.A. N.A. 0 N.A. 0 N.A. N.A. 0 0 13.3
P-Site Similarity: 100 33.3 0 26.6 N.A. 0 26.6 N.A. N.A. 0 N.A. 0 N.A. N.A. 0 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 28 19 10 10 0 10 0 10 0 0 10 19 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 19 0 % F
% Gly: 19 10 0 0 19 10 0 0 0 0 0 10 0 0 0 % G
% His: 10 10 0 0 0 0 0 0 10 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 10 19 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 10 19 28 10 19 0 10 10 10 0 % P
% Gln: 10 0 10 0 10 0 10 0 10 0 0 10 0 0 0 % Q
% Arg: 0 10 10 10 0 0 10 0 0 0 10 0 0 0 0 % R
% Ser: 10 0 0 10 0 10 0 10 0 0 10 0 19 0 19 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _