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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX1-2
All Species:
3.64
Human Site:
S21
Identified Species:
8
UniProt:
Q9UD57
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UD57
XP_002343058.1
332
34708
S21
S
H
H
K
I
S
F
S
V
L
D
I
L
D
P
Chimpanzee
Pan troglodytes
XP_521630
398
41798
A44
P
E
P
R
Q
A
A
A
A
Q
R
L
I
V
P
Rhesus Macaque
Macaca mulatta
Q2VL87
297
30903
S13
L
G
V
K
V
E
D
S
A
F
G
K
P
A
G
Dog
Lupus familis
XP_544059
354
36219
A24
P
Q
A
S
P
S
A
A
V
P
D
P
A
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P42580
305
31994
P13
D
V
G
A
K
A
A
P
S
H
H
K
I
S
F
Rat
Rattus norvegicus
P63156
327
35117
L28
A
L
P
K
G
D
P
L
L
G
D
C
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19601
232
25205
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q98876
276
29946
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
P15858
74
8968
Nematode Worm
Caenorhab. elegans
P53547
132
14911
Sea Urchin
Strong. purpuratus
NP_001009577
432
47583
S130
P
P
K
L
T
P
F
S
V
L
D
I
L
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.3
26.5
60.1
N.A.
69.8
26.5
N.A.
N.A.
38.8
N.A.
22.8
N.A.
N.A.
20.1
20.4
29.8
Protein Similarity:
100
71.1
34.9
65.8
N.A.
75.3
35.8
N.A.
N.A.
43
N.A.
35.8
N.A.
N.A.
21.3
23.7
40.5
P-Site Identity:
100
6.6
13.3
26.6
N.A.
0
20
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
0
0
60
P-Site Similarity:
100
40
20
33.3
N.A.
13.3
33.3
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
0
0
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
19
28
19
19
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
0
0
0
0
10
10
0
0
0
37
0
0
19
0
% D
% Glu:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
19
0
0
10
0
0
0
0
10
% F
% Gly:
0
10
10
0
10
0
0
0
0
10
10
0
0
0
10
% G
% His:
0
10
10
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
19
19
0
0
% I
% Lys:
0
0
10
28
10
0
0
0
0
0
0
19
0
0
0
% K
% Leu:
10
10
0
10
0
0
0
10
10
19
0
10
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
28
10
19
0
10
10
10
10
0
10
0
10
10
10
46
% P
% Gln:
0
10
0
0
10
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% R
% Ser:
10
0
0
10
0
19
0
28
10
0
0
0
0
19
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
10
0
10
0
0
0
28
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _