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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKX1-2 All Species: 0
Human Site: S78 Identified Species: 0
UniProt: Q9UD57 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UD57 XP_002343058.1 332 34708 S78 P G Q G F A A S L L T R Q A H
Chimpanzee Pan troglodytes XP_521630 398 41798 G144 S L A E V E A G K D A S S R D
Rhesus Macaque Macaca mulatta Q2VL87 297 30903 A73 K P G A K E S A L A P S E G A
Dog Lupus familis XP_544059 354 36219 G95 S L A E A D A G K D A S P G D
Cat Felis silvestris
Mouse Mus musculus P42580 305 31994 Q68 S G N P I G S Q E T P D A V G
Rat Rattus norvegicus P63156 327 35117 A87 P G Q L S A P A Q S R T V T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P19601 232 25205 G17 R R C T H P G G E R R G G S G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q98876 276 29946 L61 A G T A Y A Q L A S Y S Y H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera P15858 74 8968
Nematode Worm Caenorhab. elegans P53547 132 14911
Sea Urchin Strong. purpuratus NP_001009577 432 47583 R195 P G R L L A V R P R S S P G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.3 26.5 60.1 N.A. 69.8 26.5 N.A. N.A. 38.8 N.A. 22.8 N.A. N.A. 20.1 20.4 29.8
Protein Similarity: 100 71.1 34.9 65.8 N.A. 75.3 35.8 N.A. N.A. 43 N.A. 35.8 N.A. N.A. 21.3 23.7 40.5
P-Site Identity: 100 6.6 6.6 6.6 N.A. 6.6 26.6 N.A. N.A. 0 N.A. 13.3 N.A. N.A. 0 0 20
P-Site Similarity: 100 6.6 26.6 6.6 N.A. 13.3 33.3 N.A. N.A. 6.6 N.A. 20 N.A. N.A. 0 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 19 10 37 28 19 10 10 19 0 10 10 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 19 0 10 0 0 19 % D
% Glu: 0 0 0 19 0 19 0 0 19 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 46 10 10 0 10 10 28 0 0 0 10 10 28 19 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 10 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 10 0 0 0 19 0 0 0 0 0 0 % K
% Leu: 0 19 0 19 10 0 0 10 19 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 28 10 0 10 0 10 10 0 10 0 19 0 19 0 10 % P
% Gln: 0 0 19 0 0 0 10 10 10 0 0 0 10 0 0 % Q
% Arg: 10 10 10 0 0 0 0 10 0 19 19 10 0 10 0 % R
% Ser: 28 0 0 0 10 0 19 10 0 19 10 46 10 10 10 % S
% Thr: 0 0 10 10 0 0 0 0 0 10 10 10 0 10 0 % T
% Val: 0 0 0 0 10 0 10 0 0 0 0 0 10 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _