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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AASS All Species: 14.24
Human Site: S474 Identified Species: 24.1
UniProt: Q9UDR5 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UDR5 NP_005754.2 926 102132 S474 E S R E R A Q S L S M G T R R
Chimpanzee Pan troglodytes XP_001145257 926 102132 S474 E S R E R A Q S L S M G T R R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539546 1064 117484 S612 E S R E L A Q S L S M G T K K
Cat Felis silvestris
Mouse Mus musculus Q99K67 926 102956 F474 E S R E R I Q F L S M S T K K
Rat Rattus norvegicus A2VCW9 926 102889 F474 E S R E R I Q F L S M S T K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416001 928 102935 S475 E S R E Y A Q S L S M G N K K
Frog Xenopus laevis NP_001085980 927 103014 L474 E S R E H A Q L M T Q G T K K
Zebra Danio Brachydanio rerio XP_684074 935 104122 I482 E R R E S E Q I L K K G G M K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609150 928 103106 R473 E S Q S H R S R H K M E G S S
Honey Bee Apis mellifera XP_624513 918 102182 H464 L L N H R C K H K A D D K A Q
Nematode Worm Caenorhab. elegans NP_499884 934 103733 S479 K D K A A S A S A N S R V M G
Sea Urchin Strong. purpuratus XP_797286 940 104666 P491 D K I D P R I P I D M A T A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SMZ4 1064 117131 A469 E A Q D N I I A N G V S S Q R
Baker's Yeast Sacchar. cerevisiae P38999 446 48899 L36 V T V A C R T L A N A Q A L A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 78.5 N.A. 87.4 87.1 N.A. N.A. 74.4 72.9 65.6 N.A. 50.3 51.4 47.7 49.6
Protein Similarity: 100 99.8 N.A. 82.5 N.A. 92.8 92.7 N.A. N.A. 85.7 84.6 80.1 N.A. 70.6 70.5 67.7 67.8
P-Site Identity: 100 100 N.A. 80 N.A. 66.6 66.6 N.A. N.A. 73.3 53.3 40 N.A. 20 6.6 6.6 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 80 80 N.A. N.A. 86.6 80 46.6 N.A. 26.6 26.6 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 31.9 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 31.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 15 8 36 8 8 15 8 8 8 8 15 8 % A
% Cys: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 15 0 0 0 0 0 8 8 8 0 0 0 % D
% Glu: 72 0 0 58 0 8 0 0 0 0 0 8 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 43 15 0 8 % G
% His: 0 0 0 8 15 0 0 8 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 22 15 8 8 0 0 0 0 0 0 % I
% Lys: 8 8 8 0 0 0 8 0 8 15 8 0 8 36 43 % K
% Leu: 8 8 0 0 8 0 0 15 50 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 58 0 0 15 0 % M
% Asn: 0 0 8 0 8 0 0 0 8 15 0 0 8 0 0 % N
% Pro: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 15 0 0 0 58 0 0 0 8 8 0 8 8 % Q
% Arg: 0 8 58 0 36 22 0 8 0 0 0 8 0 15 22 % R
% Ser: 0 58 0 8 8 8 8 36 0 43 8 22 8 8 8 % S
% Thr: 0 8 0 0 0 0 8 0 0 8 0 0 50 0 0 % T
% Val: 8 0 8 0 0 0 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _