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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AASS All Species: 26.97
Human Site: Y498 Identified Species: 45.64
UniProt: Q9UDR5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UDR5 NP_005754.2 926 102132 Y498 I S E P V L E Y L S R D G N I
Chimpanzee Pan troglodytes XP_001145257 926 102132 Y498 V S E P V L E Y L S R D G N I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539546 1064 117484 Y636 V S E P V L E Y L S R D N R I
Cat Felis silvestris
Mouse Mus musculus Q99K67 926 102956 Y498 V S G P V L E Y L S R D N N I
Rat Rattus norvegicus A2VCW9 926 102889 Y498 V S G P V L E Y L S R G N N I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416001 928 102935 Y499 V S G P V L E Y L T R D S D V
Frog Xenopus laevis NP_001085980 927 103014 Y498 V S G P V I N Y L T R D P N V
Zebra Danio Brachydanio rerio XP_684074 935 104122 Y506 V S G P V I E Y L T R D A G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609150 928 103106 P497 G A G M V S A P L V E W L H R
Honey Bee Apis mellifera XP_624513 918 102182 V488 G H V S G P L V E Y L H R D N
Nematode Worm Caenorhab. elegans NP_499884 934 103733 G503 L G A G M V S G P F A D F Y S
Sea Urchin Strong. purpuratus XP_797286 940 104666 D515 M M V P P V I D Y L T R D N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SMZ4 1064 117131 L493 G H L F D K F L I N E A L D M
Baker's Yeast Sacchar. cerevisiae P38999 446 48899 A60 L D V T D D S A L D K V L A D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 78.5 N.A. 87.4 87.1 N.A. N.A. 74.4 72.9 65.6 N.A. 50.3 51.4 47.7 49.6
Protein Similarity: 100 99.8 N.A. 82.5 N.A. 92.8 92.7 N.A. N.A. 85.7 84.6 80.1 N.A. 70.6 70.5 67.7 67.8
P-Site Identity: 100 93.3 N.A. 80 N.A. 80 73.3 N.A. N.A. 60 53.3 53.3 N.A. 13.3 0 6.6 13.3
P-Site Similarity: 100 100 N.A. 86.6 N.A. 86.6 80 N.A. N.A. 86.6 80 73.3 N.A. 26.6 6.6 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 31.9 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 31.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 8 8 0 0 8 8 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 15 8 0 8 0 8 0 58 8 22 8 % D
% Glu: 0 0 22 0 0 0 50 0 8 0 15 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 8 0 0 8 0 0 8 0 0 % F
% Gly: 22 8 43 8 8 0 0 8 0 0 0 8 15 8 0 % G
% His: 0 15 0 0 0 0 0 0 0 0 0 8 0 8 0 % H
% Ile: 8 0 0 0 0 15 8 0 8 0 0 0 0 0 36 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % K
% Leu: 15 0 8 0 0 43 8 8 72 8 8 0 22 0 0 % L
% Met: 8 8 0 8 8 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 8 0 0 8 0 0 22 43 8 % N
% Pro: 0 0 0 65 8 8 0 8 8 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 58 8 8 8 8 % R
% Ser: 0 58 0 8 0 8 15 0 0 36 0 0 8 0 15 % S
% Thr: 0 0 0 8 0 0 0 0 0 22 8 0 0 0 8 % T
% Val: 50 0 22 0 65 15 0 8 0 8 0 8 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 58 8 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _