KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AASS
All Species:
29.09
Human Site:
Y727
Identified Species:
49.23
UniProt:
Q9UDR5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UDR5
NP_005754.2
926
102132
Y727
L
L
R
G
T
L
R
Y
K
G
Y
M
K
A
L
Chimpanzee
Pan troglodytes
XP_001145257
926
102132
Y727
L
L
R
G
T
L
R
Y
K
G
Y
M
K
A
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539546
1064
117484
Y865
L
L
R
G
T
L
R
Y
Q
G
Y
A
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99K67
926
102956
Y727
L
L
R
G
T
L
R
Y
K
G
Y
S
K
A
L
Rat
Rattus norvegicus
A2VCW9
926
102889
Y727
L
L
R
G
T
L
R
Y
K
G
Y
S
K
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416001
928
102935
Y729
L
L
R
G
T
L
R
Y
K
G
Y
S
K
T
M
Frog
Xenopus laevis
NP_001085980
927
103014
Y728
L
M
R
G
T
L
R
Y
K
G
F
C
N
A
M
Zebra Danio
Brachydanio rerio
XP_684074
935
104122
F736
L
I
R
G
T
L
R
F
R
G
F
S
S
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609150
928
103106
R731
T
L
L
R
G
T
I
R
Y
K
G
F
S
E
S
Honey Bee
Apis mellifera
XP_624513
918
102182
F720
I
L
R
G
T
L
R
F
K
G
F
A
N
T
I
Nematode Worm
Caenorhab. elegans
NP_499884
934
103733
Y737
I
I
R
G
T
L
R
Y
Q
G
F
V
D
T
V
Sea Urchin
Strong. purpuratus
XP_797286
940
104666
R746
N
I
I
R
G
T
L
R
Y
K
G
Y
C
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SMZ4
1064
117131
L853
T
T
I
F
R
G
T
L
R
Y
E
G
F
S
M
Baker's Yeast
Sacchar. cerevisiae
P38999
446
48899
N278
F
S
K
P
I
A
W
N
E
A
L
K
Q
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
78.5
N.A.
87.4
87.1
N.A.
N.A.
74.4
72.9
65.6
N.A.
50.3
51.4
47.7
49.6
Protein Similarity:
100
99.8
N.A.
82.5
N.A.
92.8
92.7
N.A.
N.A.
85.7
84.6
80.1
N.A.
70.6
70.5
67.7
67.8
P-Site Identity:
100
100
N.A.
80
N.A.
93.3
93.3
N.A.
N.A.
80
66.6
53.3
N.A.
6.6
53.3
46.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
86.6
N.A.
6.6
80
86.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
31.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
0
15
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% E
% Phe:
8
0
0
8
0
0
0
15
0
0
29
8
8
0
0
% F
% Gly:
0
0
0
72
15
8
0
0
0
72
15
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
15
22
15
0
8
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
50
15
0
8
36
0
0
% K
% Leu:
58
58
8
0
0
72
8
8
0
0
8
0
0
0
43
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
15
0
0
29
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
15
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
15
0
0
0
8
0
0
% Q
% Arg:
0
0
72
15
8
0
72
15
15
0
0
0
8
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
0
0
29
15
8
8
% S
% Thr:
15
8
0
0
72
15
8
0
0
0
0
0
0
22
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
15
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
15
8
43
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _