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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KL All Species: 20.3
Human Site: S1004 Identified Species: 40.61
UniProt: Q9UEF7 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UEF7 NP_004786.2 1012 116181 S1004 L S L I F Y Y S K K G R R S Y
Chimpanzee Pan troglodytes XP_522655 1012 116155 S1004 L S L I F Y Y S K K G R R S Y
Rhesus Macaque Macaca mulatta XP_001101127 1014 116467 S1006 L S L I F Y Y S K K G R R R Y
Dog Lupus familis XP_536257 1037 119179 H1018 L S S I T I L H K R K R R K I
Cat Felis silvestris
Mouse Mus musculus O35082 1014 116407 S1006 L A L I F H Y S K K G Q R S Y
Rat Rattus norvegicus Q9Z2Y9 1014 116781 S1006 L A L I Y Y Y S K K G R R R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510981 772 89021 K765 P G G G G K D K R L S G I L P
Chicken Gallus gallus XP_417105 999 114425 S991 I F C I M Y Y S K R A E R R Y
Frog Xenopus laevis NP_001106299 607 69234 K600 V F Y R K L A K K P K M S N F
Zebra Danio Brachydanio rerio XP_690797 990 113270 F981 C L V I Y Y A F K R H K L T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201398 543 61425 M536 T T M M T T G M A N A P K A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIW4 490 56058 E483 M K F L K G D E E N K G K K E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.2 45.1 N.A. 85.6 84.6 N.A. 58.2 70.7 24.1 51.1 N.A. N.A. N.A. N.A. 25.1
Protein Similarity: 100 99.4 98.6 63.8 N.A. 91.6 91 N.A. 66.1 82.8 35.6 68.2 N.A. N.A. N.A. N.A. 36.2
P-Site Identity: 100 100 93.3 40 N.A. 80 80 N.A. 0 46.6 6.6 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 46.6 N.A. 100 93.3 N.A. 6.6 60 26.6 53.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 33.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 0 17 0 9 0 17 0 0 9 0 % A
% Cys: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 9 0 0 9 0 0 9 % E
% Phe: 0 17 9 0 34 0 0 9 0 0 0 0 0 0 9 % F
% Gly: 0 9 9 9 9 9 9 0 0 0 42 17 0 0 0 % G
% His: 0 0 0 0 0 9 0 9 0 0 9 0 0 0 0 % H
% Ile: 9 0 0 67 0 9 0 0 0 0 0 0 9 0 9 % I
% Lys: 0 9 0 0 17 9 0 17 75 42 25 9 17 17 0 % K
% Leu: 50 9 42 9 0 9 9 0 0 9 0 0 9 9 9 % L
% Met: 9 0 9 9 9 0 0 9 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 17 0 0 0 9 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 9 0 9 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 0 9 25 0 42 59 25 0 % R
% Ser: 0 34 9 0 0 0 0 50 0 0 9 0 9 25 0 % S
% Thr: 9 9 0 0 17 9 0 0 0 0 0 0 0 9 9 % T
% Val: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 17 50 50 0 0 0 0 0 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _