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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KL
All Species:
27.27
Human Site:
Y497
Identified Species:
54.55
UniProt:
Q9UEF7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UEF7
NP_004786.2
1012
116181
Y497
P
K
S
S
A
L
F
Y
Q
K
L
I
E
K
N
Chimpanzee
Pan troglodytes
XP_522655
1012
116155
Y497
P
K
S
S
A
L
F
Y
Q
K
L
I
E
K
N
Rhesus Macaque
Macaca mulatta
XP_001101127
1014
116467
Y499
P
K
S
S
A
L
F
Y
Q
K
L
I
E
K
N
Dog
Lupus familis
XP_536257
1037
119179
Y499
P
K
S
S
A
Y
Y
Y
K
Q
I
I
Q
E
N
Cat
Felis silvestris
Mouse
Mus musculus
O35082
1014
116407
Y499
P
K
S
S
A
L
F
Y
Q
K
L
I
E
D
N
Rat
Rattus norvegicus
Q9Z2Y9
1014
116781
Y499
P
K
S
S
A
L
F
Y
Q
K
L
I
E
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510981
772
89021
K309
V
A
G
V
V
T
P
K
R
E
P
H
C
V
D
Chicken
Gallus gallus
XP_417105
999
114425
Y479
P
K
S
S
V
L
F
Y
Q
K
L
I
E
K
N
Frog
Xenopus laevis
NP_001106299
607
69234
T143
S
R
I
L
P
D
G
T
R
N
F
V
N
E
A
Zebra Danio
Brachydanio rerio
XP_690797
990
113270
Q477
I
E
K
N
G
F
P
Q
L
P
E
N
R
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201398
543
61425
D80
G
K
G
E
S
I
W
D
T
F
T
H
E
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIW4
490
56058
F27
N
F
P
S
T
F
T
F
G
V
A
T
S
A
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.2
45.1
N.A.
85.6
84.6
N.A.
58.2
70.7
24.1
51.1
N.A.
N.A.
N.A.
N.A.
25.1
Protein Similarity:
100
99.4
98.6
63.8
N.A.
91.6
91
N.A.
66.1
82.8
35.6
68.2
N.A.
N.A.
N.A.
N.A.
36.2
P-Site Identity:
100
100
100
53.3
N.A.
93.3
93.3
N.A.
0
93.3
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
93.3
26.6
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
50
0
0
0
0
0
9
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
9
0
9
0
0
0
0
0
9
9
% D
% Glu:
0
9
0
9
0
0
0
0
0
9
9
0
59
17
0
% E
% Phe:
0
9
0
0
0
17
50
9
0
9
9
0
0
0
0
% F
% Gly:
9
0
17
0
9
0
9
0
9
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
9
0
9
0
0
9
0
0
0
0
9
59
0
0
0
% I
% Lys:
0
67
9
0
0
0
0
9
9
50
0
0
0
34
0
% K
% Leu:
0
0
0
9
0
50
0
0
9
0
50
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
0
9
0
9
9
9
59
% N
% Pro:
59
0
9
0
9
0
17
0
0
9
9
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
9
50
9
0
0
9
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
17
0
0
0
9
0
0
% R
% Ser:
9
0
59
67
9
0
0
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
0
0
9
9
9
9
9
0
9
9
0
0
0
% T
% Val:
9
0
0
9
17
0
0
0
0
9
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
59
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _