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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VTI1B All Species: 27.88
Human Site: S197 Identified Species: 55.76
UniProt: Q9UEU0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UEU0 NP_006361.1 232 26688 S197 K S R K I L R S M S R K V T T
Chimpanzee Pan troglodytes XP_517549 231 26464 S196 K S R K I L H S M S R K A T T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537489 232 26677 S197 K S R K I L R S M S R K V T T
Cat Felis silvestris
Mouse Mus musculus O88384 232 26695 S197 K S R K I L R S M S R K V I T
Rat Rattus norvegicus P58200 232 26685 S197 K S R K I L R S M S R K V I T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513273 244 28059 G210 R S S R I L T G L L R R I I Q
Chicken Gallus gallus XP_421192 232 26789 S197 K S R K I L R S M S R R I A T
Frog Xenopus laevis NP_001084318 194 22557 L160 G Q N I L E N L S Q D R E K I
Zebra Danio Brachydanio rerio NP_957330 225 25872 A191 R S R K I L R A M S R R I V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792191 279 31523 S245 R S K R I L N S M A R R V I T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVP9 221 25007 T187 G K S K K I L T T M T R R M N
Baker's Yeast Sacchar. cerevisiae Q04338 217 24650 T182 Y V D K S I K T L K T M T R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 N.A. 95.6 N.A. 92.2 91.8 N.A. 27.8 76.2 25.8 59.4 N.A. N.A. N.A. N.A. 31.1
Protein Similarity: 100 94.4 N.A. 97.8 N.A. 96.5 96.5 N.A. 52 86.6 50 78.4 N.A. N.A. N.A. N.A. 50.9
P-Site Identity: 100 86.6 N.A. 100 N.A. 93.3 93.3 N.A. 26.6 80 0 66.6 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 86.6 N.A. 100 N.A. 93.3 93.3 N.A. 60 93.3 13.3 93.3 N.A. N.A. N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 27.5 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 9 0 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 75 17 0 0 0 0 0 0 25 34 9 % I
% Lys: 50 9 9 75 9 0 9 0 0 9 0 42 0 9 0 % K
% Leu: 0 0 0 0 9 75 9 9 17 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 67 9 0 9 0 9 0 % M
% Asn: 0 0 9 0 0 0 17 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 9 % Q
% Arg: 25 0 59 17 0 0 50 0 0 0 75 50 9 9 9 % R
% Ser: 0 75 17 0 9 0 0 59 9 59 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 17 9 0 17 0 9 25 67 % T
% Val: 0 9 0 0 0 0 0 0 0 0 0 0 42 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _