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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VTI1B All Species: 35.45
Human Site: T143 Identified Species: 70.91
UniProt: Q9UEU0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UEU0 NP_006361.1 232 26688 T143 T E S L N R A T Q S I E R S H
Chimpanzee Pan troglodytes XP_517549 231 26464 T142 P E S L N R A T Q S I E R S H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537489 232 26677 T143 T D S L N R A T Q S I E R S H
Cat Felis silvestris
Mouse Mus musculus O88384 232 26695 T143 T E S L N R A T Q S I E R S H
Rat Rattus norvegicus P58200 232 26685 T143 T E S L N R A T Q S I E R S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513273 244 28059 S156 T E R L E R S S R R L E A G Y
Chicken Gallus gallus XP_421192 232 26789 S143 T E S L N R A S Q S I E R S H
Frog Xenopus laevis NP_001084318 194 22557 D107 R N E L L G D D G N S S E S Q
Zebra Danio Brachydanio rerio NP_957330 225 25872 S137 T E S L N N A S K S I E R S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792191 279 31523 S107 I E S L N R T S Q S L D R T Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVP9 221 25007 T134 T D H L G R T T D R I K D S R
Baker's Yeast Sacchar. cerevisiae Q04338 217 24650 Q128 L S N H A I L Q K S G D R L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 N.A. 95.6 N.A. 92.2 91.8 N.A. 27.8 76.2 25.8 59.4 N.A. N.A. N.A. N.A. 31.1
Protein Similarity: 100 94.4 N.A. 97.8 N.A. 96.5 96.5 N.A. 52 86.6 50 78.4 N.A. N.A. N.A. N.A. 50.9
P-Site Identity: 100 93.3 N.A. 93.3 N.A. 100 100 N.A. 33.3 93.3 13.3 73.3 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 93.3 N.A. 100 N.A. 100 100 N.A. 66.6 100 20 86.6 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 27.5 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 40 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 59 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 0 0 9 9 9 0 0 17 9 0 0 % D
% Glu: 0 67 9 0 9 0 0 0 0 0 0 67 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 9 0 0 9 0 9 0 0 9 0 % G
% His: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 50 % H
% Ile: 9 0 0 0 0 9 0 0 0 0 67 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 17 0 0 9 0 0 9 % K
% Leu: 9 0 0 92 9 0 9 0 0 0 17 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 9 0 67 9 0 0 0 9 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 59 0 0 0 0 0 25 % Q
% Arg: 9 0 9 0 0 75 0 0 9 17 0 0 75 0 9 % R
% Ser: 0 9 67 0 0 0 9 34 0 75 9 9 0 75 0 % S
% Thr: 67 0 0 0 0 0 17 50 0 0 0 0 0 9 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _