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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VTI1B All Species: 21.82
Human Site: Y115 Identified Species: 43.64
UniProt: Q9UEU0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UEU0 NP_006361.1 232 26688 Y115 G D M K Y G I Y A V E N E H M
Chimpanzee Pan troglodytes XP_517549 231 26464 Y114 G D M K Y D I Y A V E N E H M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537489 232 26677 Y115 G D M K Y G S Y A V E N E H M
Cat Felis silvestris
Mouse Mus musculus O88384 232 26695 Y115 G D L K Y G T Y T L E N E H L
Rat Rattus norvegicus P58200 232 26685 Y115 G D L K F G T Y T L E N E H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513273 244 28059 N128 A Y S D E V R N E L L G D D G
Chicken Gallus gallus XP_421192 232 26789 F115 G D M K Y G I F S T E N E Q S
Frog Xenopus laevis NP_001084318 194 22557 Q79 N R M R S Y K Q E L G K L D A
Zebra Danio Brachydanio rerio NP_957330 225 25872 Y109 G D S R L G V Y A S Q N D Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792191 279 31523 Y79 E L L S G G M Y S A K S D F E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVP9 221 25007 E106 T A R D E L L E A G M A D T L
Baker's Yeast Sacchar. cerevisiae Q04338 217 24650 R100 S L V D S G D R D R L F G D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 N.A. 95.6 N.A. 92.2 91.8 N.A. 27.8 76.2 25.8 59.4 N.A. N.A. N.A. N.A. 31.1
Protein Similarity: 100 94.4 N.A. 97.8 N.A. 96.5 96.5 N.A. 52 86.6 50 78.4 N.A. N.A. N.A. N.A. 50.9
P-Site Identity: 100 93.3 N.A. 93.3 N.A. 66.6 60 N.A. 0 66.6 6.6 40 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 N.A. 93.3 N.A. 86.6 86.6 N.A. 13.3 80 20 66.6 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 27.5 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 0 0 42 9 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 59 0 25 0 9 9 0 9 0 0 0 34 25 0 % D
% Glu: 9 0 0 0 17 0 0 9 17 0 50 0 50 0 9 % E
% Phe: 0 0 0 0 9 0 0 9 0 0 0 9 0 9 0 % F
% Gly: 59 0 0 0 9 67 0 0 0 9 9 9 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 42 0 % H
% Ile: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 50 0 0 9 0 0 0 9 9 0 0 0 % K
% Leu: 0 17 25 0 9 9 9 0 0 34 17 0 9 0 34 % L
% Met: 0 0 42 0 0 0 9 0 0 0 9 0 0 0 25 % M
% Asn: 9 0 0 0 0 0 0 9 0 0 0 59 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 9 0 0 17 0 % Q
% Arg: 0 9 9 17 0 0 9 9 0 9 0 0 0 0 0 % R
% Ser: 9 0 17 9 17 0 9 0 17 9 0 9 0 0 17 % S
% Thr: 9 0 0 0 0 0 17 0 17 9 0 0 0 9 0 % T
% Val: 0 0 9 0 0 9 9 0 0 25 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 42 9 0 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _