KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK39
All Species:
27.88
Human Site:
S373
Identified Species:
51.11
UniProt:
Q9UEW8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UEW8
NP_037365.2
547
59642
S373
V
R
R
V
P
G
S
S
G
H
L
H
K
T
E
Chimpanzee
Pan troglodytes
XP_515880
720
78003
S546
V
R
R
V
P
G
S
S
G
H
L
H
K
T
E
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
S327
S
E
E
D
E
M
D
S
G
T
M
V
R
A
V
Dog
Lupus familis
XP_535944
666
73491
S493
V
R
R
V
P
G
S
S
G
H
L
H
K
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1W9
556
60301
S383
V
R
R
V
P
G
S
S
G
H
L
H
K
T
E
Rat
Rattus norvegicus
O88506
553
60032
S380
V
R
R
V
P
G
S
S
G
H
L
H
K
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513780
525
58469
S352
V
R
R
V
P
G
S
S
G
H
L
H
K
T
E
Chicken
Gallus gallus
XP_422019
453
50652
R293
R
T
P
N
I
A
Q
R
A
K
K
V
R
R
V
Frog
Xenopus laevis
Q6PA14
485
55246
V325
E
N
V
N
E
D
E
V
D
V
G
T
M
V
Q
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
S331
H
T
M
V
K
S
G
S
E
S
A
G
T
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477308
552
60283
G377
S
A
T
G
S
G
T
G
D
R
K
H
P
S
S
Honey Bee
Apis mellifera
XP_396480
690
76398
S526
S
K
R
Q
P
G
T
S
G
R
L
H
R
T
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791076
537
59936
R364
G
S
S
G
R
L
H
R
T
V
D
G
A
W
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
27.4
73.5
N.A.
96
96.3
N.A.
89.7
79.8
27.9
28.3
N.A.
56.8
47.3
N.A.
54.3
Protein Similarity:
100
75
45.1
76.5
N.A.
96.4
96.9
N.A.
92.3
81.5
46.2
45.3
N.A.
71.7
59.1
N.A.
71.6
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
100
0
0
13.3
N.A.
13.3
53.3
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
100
6.6
6.6
13.3
N.A.
26.6
73.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
0
8
0
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
8
0
16
0
8
0
0
0
0
% D
% Glu:
8
8
8
0
16
0
8
0
8
0
0
0
0
0
54
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
16
0
62
8
8
62
0
8
16
0
0
0
% G
% His:
8
0
0
0
0
0
8
0
0
47
0
62
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
0
0
8
16
0
47
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
54
0
0
0
0
% L
% Met:
0
0
8
0
0
8
0
0
0
0
8
0
8
8
0
% M
% Asn:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
54
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
8
47
54
0
8
0
0
16
0
16
0
0
24
8
8
% R
% Ser:
24
8
8
0
8
8
47
70
0
8
0
0
0
8
8
% S
% Thr:
0
16
8
0
0
0
16
0
8
8
0
8
8
54
0
% T
% Val:
47
0
8
54
0
0
0
8
0
16
0
16
0
8
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _