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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK39
All Species:
1.52
Human Site:
S420
Identified Species:
2.78
UniProt:
Q9UEW8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UEW8
NP_037365.2
547
59642
S420
E
N
P
E
I
A
V
S
A
S
T
I
P
E
Q
Chimpanzee
Pan troglodytes
XP_515880
720
78003
N593
E
N
P
E
I
A
V
N
A
S
T
I
P
E
Q
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
D374
T
M
V
I
N
T
E
D
E
E
E
E
G
T
M
Dog
Lupus familis
XP_535944
666
73491
N540
E
N
P
E
M
A
V
N
A
S
S
I
P
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1W9
556
60301
N430
E
N
S
E
I
S
V
N
A
G
G
I
P
E
Q
Rat
Rattus norvegicus
O88506
553
60032
N427
E
N
P
E
I
S
V
N
A
G
G
I
P
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513780
525
58469
N399
E
N
P
D
I
S
V
N
V
S
S
I
P
E
Q
Chicken
Gallus gallus
XP_422019
453
50652
R340
V
S
Q
E
K
S
R
R
V
K
E
E
E
N
T
Frog
Xenopus laevis
Q6PA14
485
55246
D372
M
G
T
M
L
I
N
D
E
D
E
E
E
E
T
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
L378
D
E
E
E
E
E
D
L
G
S
M
R
R
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477308
552
60283
P424
V
S
S
A
T
V
T
P
G
A
P
A
A
A
G
Honey Bee
Apis mellifera
XP_396480
690
76398
E573
S
S
S
D
E
D
E
E
E
F
F
G
R
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791076
537
59936
T411
E
N
E
M
G
T
K
T
E
T
E
S
I
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
27.4
73.5
N.A.
96
96.3
N.A.
89.7
79.8
27.9
28.3
N.A.
56.8
47.3
N.A.
54.3
Protein Similarity:
100
75
45.1
76.5
N.A.
96.4
96.9
N.A.
92.3
81.5
46.2
45.3
N.A.
71.7
59.1
N.A.
71.6
P-Site Identity:
100
93.3
0
80
N.A.
66.6
73.3
N.A.
66.6
6.6
6.6
13.3
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
0
100
N.A.
80
86.6
N.A.
93.3
20
13.3
20
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
24
0
0
39
8
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
16
0
8
8
16
0
8
0
0
0
0
8
% D
% Glu:
54
8
16
54
16
8
16
8
31
8
31
24
16
54
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
16
16
16
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
39
8
0
0
0
0
0
47
8
0
0
% I
% Lys:
0
0
0
0
8
0
8
0
0
8
0
0
0
8
8
% K
% Leu:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% L
% Met:
8
8
0
16
8
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
54
0
0
8
0
8
39
0
0
0
0
0
16
0
% N
% Pro:
0
0
39
0
0
0
0
8
0
0
8
0
47
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
47
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
0
8
16
0
0
% R
% Ser:
8
24
24
0
0
31
0
8
0
39
16
8
0
0
0
% S
% Thr:
8
0
8
0
8
16
8
8
0
8
16
0
0
8
16
% T
% Val:
16
0
8
0
0
8
47
0
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _