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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADD3 All Species: 35.15
Human Site: S592 Identified Species: 70.3
UniProt: Q9UEY8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UEY8 NP_001112.2 706 79155 S592 S D D A S S V S Q I Q S Q T Q
Chimpanzee Pan troglodytes XP_001141198 706 79136 S592 S D D A S S V S Q I Q S Q T Q
Rhesus Macaque Macaca mulatta XP_001084569 705 79180 S591 S D D A S S V S Q I Q S Q T Q
Dog Lupus familis XP_544011 706 79076 S592 S D D A S S V S Q I Q S Q T Q
Cat Felis silvestris
Mouse Mus musculus Q9QYB5 706 78745 S592 S D D A A S V S Q I Q S Q T Q
Rat Rattus norvegicus Q62847 705 78785 S592 S D D A A S V S Q I Q S Q T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512778 707 79109 S593 S D D G S S V S Q V Q S Q T Q
Chicken Gallus gallus NP_989434 709 78787 S593 S D G G S S V S Q I Q S Q T Q
Frog Xenopus laevis NP_001085075 687 76338 T586 D A A P I V I T Q S P P Q T P
Zebra Danio Brachydanio rerio NP_955957 672 75335 L569 I D A D E E Q L T S D D A S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02645 1156 127921 T826 V V T S T H P T Q C Q S Q S Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U9K0 732 82151 M616 E A D T V S L M Q G V R E H K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 95.6 96.7 N.A. 92 92.2 N.A. 90.2 85.3 69.8 67.8 N.A. 23.1 N.A. 28.4 N.A.
Protein Similarity: 100 100 97.7 98.8 N.A. 96.7 97.3 N.A. 96.8 92 80.8 82 N.A. 40.3 N.A. 51 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 86.6 20 6.6 N.A. 33.3 N.A. 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 86.6 33.3 13.3 N.A. 60 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 17 50 17 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 9 75 67 9 0 0 0 0 0 0 9 9 0 0 0 % D
% Glu: 9 0 0 0 9 9 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 17 0 0 0 0 0 9 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % H
% Ile: 9 0 0 0 9 0 9 0 0 59 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 9 0 0 0 9 9 0 0 9 % P
% Gln: 0 0 0 0 0 0 9 0 92 0 75 0 84 0 75 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 67 0 0 9 50 75 0 67 0 17 0 75 0 17 0 % S
% Thr: 0 0 9 9 9 0 0 17 9 0 0 0 0 75 9 % T
% Val: 9 9 0 0 9 9 67 0 0 9 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _