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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHB1 All Species: 21.82
Human Site: T97 Identified Species: 60
UniProt: Q9UF11 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UF11 NP_001123505.1 243 27186 T97 R S R D G L L T V N L R E G G
Chimpanzee Pan troglodytes XP_001174830 243 27168 T97 R S R D G L L T V N L R E G G
Rhesus Macaque Macaca mulatta XP_001115413 243 27297 T97 R S R D G L L T V N L R E G G
Dog Lupus familis XP_850310 242 27204 T97 R S R D G L L T V N L R E G S
Cat Felis silvestris
Mouse Mus musculus Q9QYE9 243 27322 T97 R S R D G L L T V N L R E G S
Rat Rattus norvegicus Q9WU68 223 25225 T78 R S R D G L L T V N L R E G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F3S2 224 25391 Q78 K Q R D C L L Q I V C R D G K
Frog Xenopus laevis NP_001087159 217 24374 D72 L N P P E G R D K D C C L Q I
Zebra Danio Brachydanio rerio NP_957296 223 24869 Q78 K G K D S L L Q I V C R D G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.9 95.4 N.A. 93.8 86 N.A. N.A. 40.3 36.2 35.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 98.7 96.7 N.A. 96.7 88.8 N.A. N.A. 53 48.1 49.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 40 0 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 60 13.3 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 34 12 0 0 0 % C
% Asp: 0 0 0 89 0 0 0 12 0 12 0 0 23 0 0 % D
% Glu: 0 0 0 0 12 0 0 0 0 0 0 0 67 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 0 67 12 0 0 0 0 0 0 0 89 34 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 23 0 0 0 0 0 12 % I
% Lys: 23 0 12 0 0 0 0 0 12 0 0 0 0 0 12 % K
% Leu: 12 0 0 0 0 89 89 0 0 0 67 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 67 0 0 0 0 0 % N
% Pro: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 12 0 0 0 0 0 23 0 0 0 0 0 12 0 % Q
% Arg: 67 0 78 0 0 0 12 0 0 0 0 89 0 0 12 % R
% Ser: 0 67 0 0 12 0 0 0 0 0 0 0 0 0 34 % S
% Thr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 67 23 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _