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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHB1
All Species:
23.94
Human Site:
Y193
Identified Species:
65.83
UniProt:
Q9UF11
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF11
NP_001123505.1
243
27186
Y193
A
T
Y
V
R
S
Y
Y
G
P
P
Y
A
G
P
Chimpanzee
Pan troglodytes
XP_001174830
243
27168
Y193
A
T
Y
V
R
S
Y
Y
G
P
P
Y
A
G
P
Rhesus Macaque
Macaca mulatta
XP_001115413
243
27297
Y193
A
T
Y
V
R
S
Y
Y
G
P
P
Y
A
G
P
Dog
Lupus familis
XP_850310
242
27204
Y193
A
T
Y
I
R
S
Y
Y
G
P
Y
A
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYE9
243
27322
Y193
A
T
Y
V
R
S
Y
Y
G
P
P
Y
A
G
P
Rat
Rattus norvegicus
Q9WU68
223
25225
Y174
A
T
Y
V
R
S
Y
Y
G
P
P
Y
G
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3S2
224
25391
Y174
G
Q
A
Y
D
V
P
Y
Q
Y
P
Y
H
G
P
Frog
Xenopus laevis
NP_001087159
217
24374
Y168
D
G
Q
A
Y
A
S
Y
P
Y
P
P
Q
G
Y
Zebra Danio
Brachydanio rerio
NP_957296
223
24869
Y174
G
Q
Q
Y
A
V
A
Y
P
Y
H
Y
Q
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
95.4
N.A.
93.8
86
N.A.
N.A.
40.3
36.2
35.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
98.7
96.7
N.A.
96.7
88.8
N.A.
N.A.
53
48.1
49.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
100
80
N.A.
N.A.
33.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
100
80
N.A.
N.A.
33.3
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
12
12
12
12
12
0
0
0
0
12
45
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
23
12
0
0
0
0
0
0
67
0
0
0
23
78
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
23
67
78
12
0
23
56
% P
% Gln:
0
23
23
0
0
0
0
0
12
0
0
0
23
0
0
% Q
% Arg:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
67
12
0
0
0
0
0
0
0
0
% S
% Thr:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
56
0
23
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
67
23
12
0
67
100
0
34
12
78
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _