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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
5.76
Human Site:
S145
Identified Species:
9.74
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
S145
W
S
R
R
L
L
G
S
R
L
S
G
A
F
L
Chimpanzee
Pan troglodytes
XP_524461
536
58825
S145
W
S
R
R
L
L
G
S
R
L
S
G
A
F
L
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
G90
G
G
A
F
H
L
K
G
T
G
E
L
T
R
A
Dog
Lupus familis
XP_541686
567
62920
S142
M
L
R
C
V
D
M
S
R
G
V
L
E
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
E88
Y
G
Q
F
V
A
G
E
T
A
E
E
V
R
N
Rat
Rattus norvegicus
Q2V057
456
50984
E88
Y
G
Q
F
V
A
G
E
T
A
E
E
V
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
M97
R
R
L
F
E
W
G
M
K
G
S
V
Y
G
Q
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
A97
G
E
T
E
G
E
I
A
D
S
M
Q
K
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
Q165
L
A
R
N
L
L
G
Q
K
L
F
V
L
L
M
Honey Bee
Apis mellifera
XP_395275
528
60938
R135
R
N
M
D
I
F
I
R
C
L
E
S
V
A
G
Nematode Worm
Caenorhab. elegans
O45228
616
69804
C222
F
Y
E
G
E
E
Q
C
D
K
N
R
D
I
F
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
V33
F
A
A
S
P
Q
S
V
R
Q
V
A
N
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
A131
T
F
Y
D
H
F
C
A
G
E
D
A
D
A
A
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
V108
I
P
V
I
K
F
F
V
S
S
L
Y
C
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
100
6.6
20
N.A.
6.6
6.6
N.A.
N.A.
N.A.
13.3
0
N.A.
33.3
6.6
0
6.6
P-Site Similarity:
100
100
6.6
26.6
N.A.
26.6
26.6
N.A.
N.A.
N.A.
20
6.6
N.A.
53.3
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
15
0
0
15
0
15
0
15
0
15
15
15
15
% A
% Cys:
0
0
0
8
0
0
8
8
8
0
0
0
8
0
0
% C
% Asp:
0
0
0
15
0
8
0
0
15
0
8
0
15
0
0
% D
% Glu:
0
8
8
8
15
15
0
15
0
8
29
15
8
0
0
% E
% Phe:
15
8
0
29
0
22
8
0
0
0
8
0
0
15
15
% F
% Gly:
15
22
0
8
8
0
43
8
8
22
0
15
0
15
22
% G
% His:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
8
0
15
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
8
0
15
8
0
0
8
8
0
% K
% Leu:
8
8
8
0
22
29
0
0
0
29
8
15
8
8
15
% L
% Met:
8
0
8
0
0
0
8
8
0
0
8
0
0
8
8
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
8
0
8
0
8
% N
% Pro:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
15
0
0
8
8
8
0
8
0
8
0
0
8
% Q
% Arg:
15
8
29
15
0
0
0
8
29
0
0
8
0
22
0
% R
% Ser:
0
15
0
8
0
0
8
22
8
15
22
8
0
0
8
% S
% Thr:
8
0
8
0
0
0
0
0
22
0
0
0
8
8
0
% T
% Val:
0
0
8
0
22
0
0
15
0
0
15
15
22
0
0
% V
% Trp:
15
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
8
8
0
0
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _