KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
6.67
Human Site:
S199
Identified Species:
11.28
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
S199
E
P
D
S
A
A
K
S
G
E
A
W
Y
E
G
Chimpanzee
Pan troglodytes
XP_524461
536
58825
S199
E
P
D
S
A
A
K
S
G
E
A
W
Y
E
G
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
G144
V
Y
G
Q
F
V
A
G
E
T
A
E
E
V
R
Dog
Lupus familis
XP_541686
567
62920
D196
E
R
L
A
E
A
M
D
S
G
Q
D
L
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
S142
M
L
R
C
V
D
L
S
R
A
L
V
D
A
H
Rat
Rattus norvegicus
Q2V057
456
50984
S142
M
L
H
C
V
D
L
S
R
A
V
A
D
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
N151
G
E
R
W
Y
E
Q
N
E
S
I
M
L
D
C
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
N151
H
S
N
G
W
S
N
N
P
M
M
Q
L
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
E219
D
I
T
Q
E
E
A
E
K
R
E
V
E
S
S
Honey Bee
Apis mellifera
XP_395275
528
60938
T189
G
G
E
G
A
V
L
T
H
H
A
K
P
D
D
Nematode Worm
Caenorhab. elegans
O45228
616
69804
L276
T
Q
N
F
F
K
A
L
T
G
G
M
S
L
Q
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
A87
L
D
M
Q
T
E
V
A
R
P
N
Q
P
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
L185
T
I
E
A
A
K
S
L
P
T
S
H
F
S
S
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
E162
P
V
D
Q
I
V
K
E
T
I
S
S
V
H
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
0
0
N.A.
0
13.3
0
0
P-Site Similarity:
100
100
6.6
26.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
20
26.6
N.A.
6.6
33.3
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
29
22
22
8
0
15
29
8
0
15
0
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
22
0
0
15
0
8
0
0
0
8
15
15
8
% D
% Glu:
22
8
15
0
15
22
0
15
15
15
8
8
15
15
0
% E
% Phe:
0
0
0
8
15
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
15
8
8
15
0
0
0
8
15
15
8
0
0
0
15
% G
% His:
8
0
8
0
0
0
0
0
8
8
0
8
0
8
15
% H
% Ile:
0
15
0
0
8
0
0
0
0
8
8
0
0
8
15
% I
% Lys:
0
0
0
0
0
15
22
0
8
0
0
8
0
8
0
% K
% Leu:
8
15
8
0
0
0
22
15
0
0
8
0
22
8
8
% L
% Met:
15
0
8
0
0
0
8
0
0
8
8
15
0
0
0
% M
% Asn:
0
0
15
0
0
0
8
15
0
0
8
0
0
0
8
% N
% Pro:
8
15
0
0
0
0
0
0
15
8
0
0
15
0
0
% P
% Gln:
0
8
0
29
0
0
8
0
0
0
8
15
0
8
8
% Q
% Arg:
0
8
15
0
0
0
0
0
22
8
0
0
0
0
8
% R
% Ser:
0
8
0
15
0
8
8
29
8
8
15
8
8
15
15
% S
% Thr:
15
0
8
0
8
0
0
8
15
15
0
0
0
0
0
% T
% Val:
8
8
0
0
15
22
8
0
0
0
8
15
8
8
0
% V
% Trp:
0
0
0
8
8
0
0
0
0
0
0
15
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _