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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
6.36
Human Site:
S273
Identified Species:
10.77
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
S273
R
L
A
E
A
M
D
S
G
Q
N
L
Q
V
S
Chimpanzee
Pan troglodytes
XP_524461
536
58825
S273
R
L
A
E
A
M
D
S
G
Q
S
L
Q
V
S
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
V218
A
S
L
M
Q
L
K
V
T
A
L
T
S
A
R
Dog
Lupus familis
XP_541686
567
62920
W270
G
E
G
G
P
W
V
W
N
T
Y
Q
A
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
A216
E
Q
N
Q
H
L
Q
A
S
L
S
R
L
H
R
Rat
Rattus norvegicus
Q2V057
456
50984
A216
E
Q
N
Q
H
L
Q
A
S
L
S
R
L
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
S225
F
L
S
E
G
E
N
S
H
L
R
N
S
V
R
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
R225
E
A
S
V
N
K
V
R
V
L
V
D
A
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
A293
D
D
R
K
A
P
R
A
V
A
T
G
A
T
F
Honey Bee
Apis mellifera
XP_395275
528
60938
L263
M
V
R
L
M
S
Q
L
T
S
K
E
E
E
M
Nematode Worm
Caenorhab. elegans
O45228
616
69804
G350
Q
V
L
N
I
K
T
G
S
L
E
P
L
I
Q
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
R161
H
L
K
H
A
L
K
R
I
D
T
V
V
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
E259
A
E
E
E
R
E
L
E
A
A
H
G
R
I
Q
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
L236
I
T
K
E
I
F
E
L
N
Q
S
L
L
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
93.3
0
0
N.A.
0
0
N.A.
N.A.
N.A.
26.6
0
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
100
6.6
0
N.A.
26.6
26.6
N.A.
N.A.
N.A.
40
6.6
N.A.
20
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
15
0
29
0
0
22
8
22
0
0
22
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
15
0
0
8
0
8
0
0
0
% D
% Glu:
22
15
8
36
0
15
8
8
0
0
8
8
8
15
0
% E
% Phe:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
8
8
8
0
0
8
15
0
0
15
0
0
0
% G
% His:
8
0
0
8
15
0
0
0
8
0
8
0
0
15
0
% H
% Ile:
8
0
0
0
15
0
0
0
8
0
0
0
0
15
0
% I
% Lys:
0
0
15
8
0
15
15
0
0
0
8
0
0
8
8
% K
% Leu:
0
29
15
8
0
29
8
15
0
36
8
22
29
0
8
% L
% Met:
8
0
0
8
8
15
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
15
8
8
0
8
0
15
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
15
0
15
8
0
22
0
0
22
0
8
15
8
15
% Q
% Arg:
15
0
15
0
8
0
8
15
0
0
8
15
8
0
36
% R
% Ser:
0
8
15
0
0
8
0
22
22
8
29
0
15
0
15
% S
% Thr:
0
8
0
0
0
0
8
0
15
8
15
8
0
8
0
% T
% Val:
0
15
0
8
0
0
15
8
15
0
8
8
8
22
0
% V
% Trp:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _