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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
6.97
Human Site:
S440
Identified Species:
11.79
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
S440
V
A
S
H
N
E
E
S
V
R
Q
A
T
K
R
Chimpanzee
Pan troglodytes
XP_524461
536
58825
S440
V
A
S
H
N
E
E
S
V
R
Q
A
T
K
R
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
V371
Y
L
D
K
E
R
A
V
A
Q
L
H
G
M
K
Dog
Lupus familis
XP_541686
567
62920
A436
N
R
S
V
L
Q
G
A
R
K
E
Q
T
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
T369
E
E
S
V
R
Q
A
T
K
R
M
W
E
L
G
Rat
Rattus norvegicus
Q2V057
456
50984
T369
E
E
S
I
R
Q
A
T
R
R
M
W
E
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
A378
N
E
E
S
V
L
H
A
V
T
R
M
A
E
L
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
L378
S
V
C
F
G
Q
L
L
G
M
C
D
H
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
V578
A
S
H
N
E
D
T
V
R
F
A
I
Q
Q
M
Honey Bee
Apis mellifera
XP_395275
528
60938
V425
A
S
H
N
E
D
T
V
R
F
A
I
E
K
M
Nematode Worm
Caenorhab. elegans
O45228
616
69804
V516
A
S
H
N
E
D
T
V
R
F
A
L
N
L
M
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
M314
I
E
S
V
S
K
A
M
K
R
M
W
E
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
R412
D
S
G
R
L
A
S
R
K
A
S
D
L
G
I
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
L389
Q
M
L
V
T
N
L
L
K
S
T
Q
D
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
100
0
13.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
6.6
0
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
100
13.3
40
N.A.
26.6
26.6
N.A.
N.A.
N.A.
26.6
6.6
N.A.
26.6
26.6
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
15
0
0
0
8
29
15
8
8
22
15
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
8
0
0
22
0
0
0
0
0
15
8
0
0
% D
% Glu:
15
29
8
0
29
15
15
0
0
0
8
0
29
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
22
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
8
0
8
0
0
0
8
8
22
% G
% His:
0
0
22
15
0
0
8
0
0
0
0
8
8
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
0
15
0
0
8
% I
% Lys:
0
0
0
8
0
8
0
0
29
8
0
0
0
22
8
% K
% Leu:
0
8
8
0
15
8
15
15
0
0
8
8
8
36
15
% L
% Met:
0
8
0
0
0
0
0
8
0
8
22
8
0
8
22
% M
% Asn:
15
0
0
22
15
8
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
29
0
0
0
8
15
15
8
8
0
% Q
% Arg:
0
8
0
8
15
8
0
8
36
36
8
0
0
0
15
% R
% Ser:
8
29
43
8
8
0
8
15
0
8
8
0
0
0
15
% S
% Thr:
0
0
0
0
8
0
22
15
0
8
8
0
22
0
0
% T
% Val:
15
8
0
29
8
0
0
29
22
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
22
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _